Evidence map›Paper›PMID 31072065›Full record

ReviewInternational journal of molecular sciences2019

Exogenous RNAs for Gene Regulation and Plant Resistance.

Alexandra S Dubrovina, Konstantin V Kiselev

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 179 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Targeted Suppression of the Tomato PathogenJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Hairpin-RNA spray confers resistance to mungbean yellow mosaic India virus in mungbean.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
  14. Regulation of Plant Genes with Exogenous RNAs.International journal of molecular sciences · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. RNAi spray-induced gene silencing ofFrontiers in plant science · 2025
    Article
  19. Review
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alexandra S DubrovinaLaboratory of Biotechnology, Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia. dubrovina@biosoil.ru.
Konstantin V KiselevLaboratory of Biotechnology, Federal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia. kiselev@biosoil.ru.
Far Eastern Federal University · RUFederal Scientific Center of the East Asia Terrestrial Biodiversity FEB RAS · RU

Funding

Russian Science Foundation 17-74-10083
6 · The paper itself

Abstract

Recent investigations documented that plants can uptake and process externally applied double-stranded RNAs (dsRNAs), hairpin RNAs (hpRNAs), and small interfering RNAs (siRNAs) designed to silence important genes of plant pathogenic viruses, fungi, or insects. The exogenously applied RNAs spread locally and systemically, move into the pathogens, and induce RNA interference-mediated plant pathogen resistance. Recent findings also provided examples of plant transgene and endogene post-transcriptional down-regulation by complementary dsRNAs or siRNAs applied onto the plant surfaces. Understanding the plant perception and processing of exogenous RNAs could result in the development of novel biotechnological approaches for crop protection. This review summarizes and discusses the emerging studies reporting on exogenous RNA applications for down-regulation of essential fungal and insect genes, targeting of plant viruses, or suppression of plant transgenes and endogenes for increased resistance and changed phenotypes. We also analyze the current understanding of dsRNA uptake mechanisms and dsRNA stability in plant environments.

Indexed as

Disease ResistanceGene Expression Regulation, PlantGene SilencingPlant DiseasesPlants, Genetically ModifiedRNA, Double-StrandedRNA, Small InterferingRNA, Double-StrandedRNA, Small InterferingdsRNAs, hpRNAs and siRNAsexogenous RNAsexternal applicationgene silencingplant gene regulationplant resistanceRNA interferenceRNA spraying

Identifiers

PMID31072065
PMCPMC6539981
OpenAlexW2944694838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.