Evidence map›Paper›PMID 31071536›Full record

ArticleClinical biomechanics (Bristol, Avon)2019

Paradoxical relationship in sensorimotor system: Knee joint position sense absolute error and joint stiffness measures.

Takashi Nagai, Nathaniel A Bates, Timothy E Hewett, Nathan D Schilaty

Open access · greenAbstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Takashi NagaiBiomechanics Laboratories, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Sports Medicine Center, Mayo Clinic, Rochester and Minneapolis, MN, USA. Electronic address: nagai.takashi@mayo.edu.
Nathaniel A BatesBiomechanics Laboratories, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Sports Medicine Center, Mayo Clinic, Rochester and Minneapolis, MN, USA; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Timothy E HewettBiomechanics Laboratories, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Sports Medicine Center, Mayo Clinic, Rochester and Minneapolis, MN, USA; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA; Department of Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN, USA.
Nathan D SchilatyBiomechanics Laboratories, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Sports Medicine Center, Mayo Clinic, Rochester and Minneapolis, MN, USA; Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Florida · USMayo Clinic in Arizona · US

Funding

Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female AthletesR01AR055563 · NIAMS · OHIO STATE UNIVERSITY · PI BATES, NATHANIEL ANDREW, KRYCH, AARON · 2008 to 2022
$5.9M
Multi-faceted Approach to Modeling ACL Injury MechanismsR01AR056259 · NIAMS · OHIO STATE UNIVERSITY · PI HEWETT, TIMOTHY E · 2009 to 2017
$4.9M
NIAMS NIH HHS L30 AR070273NIAMS NIH HHS R01 AR055563NIAMS NIH HHS R01 AR056259NICHD NIH HHS K12 HD065987
6 · The paper itself

Abstract

backgroundRelationships between joint position sense and the sensorimotor characteristics such as joint stiffness, time to detect motion, and time to peak torque during a perturbation test have rarely been investigated due to methodological challenges. The purpose of this study was to compare joint position sense and the sensorimotor characteristics in healthy individuals.

methodsA total of 26 subjects were recruited and completed joint position sense and a perturbation test on isokinetic dynamometer. Joint position sense was assessed by comparison of the absolute angle difference between a reference and replicated position. During the perturbation test, the dynamometer moved the knee flexion angle from 70° to 30° (0° represents a full knee extension) at the velocity of 500° per second at random. Subjects were asked to react and pull back the leg as soon as they perceived the movement. Pearson or Spearman's correlation coefficients were used to assess these relationships (P < 0.05).

findingsLarger joint position sense absolute error values were significantly correlated with higher short-range at 50 milliseconds (r = 0.572, P = 0.002), at 100 milliseconds (ρ = 0.416, P = 0.035), and reactive joint stiffness (r = 0.395, P = 0.046).

interpretationThere was a paradoxical relationship between higher joint stiffness and worsened joint position sense. Potential reasons include sensory weighting within the sensorimotor system and thixotropic properties (after-effects of muscle eccentric contractions to increase stiffness and alter joint position sense).

Indexed as

AdultFemaleHumansKnee JointMaleMovementMuscle ContractionMuscle, SkeletalProprioceptionRegression AnalysisSensory ThresholdsTorqueJoint position senseParadoxical relationshipSensorimotor systemStiffness

Identifiers

PMID31071536
PMCPMC6635082
OpenAlexW2943421974

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.