ArticleJournal of the American College of Cardiology2019
Surgery Does Not Improve Survival in Patients With Isolated Severe Tricuspid Regurgitation.
Article in Journal of the American College of Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 4 of them syntheses that pooled it.
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Who cites it
104 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Survival outcomes in isolated severe tricuspid regurgitation according to therapeutic modalities: a systematic review and meta-analysis.Open heart · 2025Pooled it
- Comparative analysis of MitraClip/TriClip and PASCAL in transcatheter tricuspid valve repair for tricuspid regurgitation: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Outcomes of isolated tricuspid valve replacement: a systematic review and meta-analysis of 5,316 patients from 35 studies.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Pooled it
- Isolated surgical tricuspid repair versus replacement: meta-analysis of 15 069 patients.Open heart · 2020Pooled it
- Prognostic value of right ventricular free-wall longitudinal strain compared to conventional echocardiographic parameters in tricuspid regurgitation: a systematic review and meta-analysis.Journal of echocardiography · 2026Article
- Transcatheter vs Surgical Tricuspid Valve Repair: An Analysis of Medicare Beneficiaries.The Annals of thoracic surgery · 2026Article
- Isolated or concomitant tricuspid valve surgery for massive or torrential tricuspid regurgitation.JTCVS open · 2026Article
- Tricuspid valve disease: updates on diagnostic imaging and intervention.Nature reviews. Cardiology · 2026Review
- Tricuspid Regurgitation: Pathophysiology, Risk Stratification, and Implications for Intervention.Journal of clinical medicine · 2026Review
- A Pathophysiology-Integrated Nomogram to Predict Tricuspid Regurgitation Progression After Isolated Mitral Valve Surgery: A Retrospective Cohort Study.Reviews in cardiovascular medicine · 2026Article
- Navigating isolated tricuspid regurgitation: A practical guide to perioperative and periprocedural management.JTCVS open · 2026Article
- Survival and Risk Profile of Patients With Significant Tricuspid Regurgitation by Etiology.Journal of the American Heart Association · 2026Article
- Transcatheter Tricuspid Valve Replacement Versus Totally Thoracoscopic Beating-Heart Surgery for Tricuspid Regurgitation.Cardiovascular drugs and therapy · 2026Article
- Tricuspid Transcatheter Edge-to-Edge Repair at a Crossroads: Prognosis-Shaping Intervention or High-Tech Palliation?Journal of clinical medicine · 2026Review
- Management of Tricuspid Valve Regurgitation Consensus Recommendations.Heart views : the official journal of the Gulf Heart Association · 2026Review
- Trends in Utilization and Outcomes of Isolated and Concomitant Tricuspid Valve Surgery in the United States.Annals of thoracic surgery short reports · 2025Article
- Isolated and Concomitant Tricuspid Valve Replacement: Long-Term Survival and Predictors of Mortality in a 25-Year Cohort.Reviews in cardiovascular medicine · 2025Article
- Temporal Trends and Prognostic Impact of Pacemaker-Associated Heart Failure: Insights from a Nationwide Cohort Study.Journal of clinical medicine · 2025Article
- Article
- Aortic valve replacement and mortality in asymptomatic individuals with severe aortic stenosis and left ventricular hypertrophy.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Article
44 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
Funding
Abstract
backgroundPatients with isolated tricuspid regurgitation (TR) in the absence of left-sided valvular dysfunction are often managed nonoperatively.
objectivesThe purpose of this study was to assess the impact of surgery for isolated TR, comparing survival for isolated severe TR patients who underwent surgery with those who did not.
methodsA longitudinal echocardiography database was used to perform a retrospective analysis of 3,276 adult patients with isolated severe TR from November 2001 to March 2016. All-cause mortality for patients who underwent surgery versus those who did not was analyzed in the entire cohort and in a propensity-matched sample. To assess the possibility of immortal time bias, the analysis was performed considering time from diagnosis to surgery as a time-dependent covariate.
resultsOf 3,276 patients with isolated severe TR, 171 (5%) underwent tricuspid valve surgery, including 143 (84%) repairs and 28 (16%) replacements. The remaining 3,105 (95%) patients were medically managed. When considering surgery as a time-dependent covariate in a propensity-matched sample, there was no difference in overall survival between patients who received medical versus surgical therapy (hazard ratio: 1.34; 95% confidence interval: 0.78 to 2.30; p = 0.288). In the subgroup that underwent surgery, there was no difference in survival between tricuspid repair versus replacement (hazard ratio: 1.53; 95% confidence interval: 0.74 to 3.17; p = 0.254).
conclusionsIn patients with isolated severe TR, surgery is not associated with improved long-term survival compared to medical management alone after accounting for immortal time bias.
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