SynthesisPloS one2019
Higher dietary acid load potentially increases serum triglyceride and obesity prevalence in adults: An updated systematic review and meta-analysis.
Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolic syndrome in relation to dietary acid load: a dose-response meta-analysis of observational studies.Frontiers in nutrition · 2023Pooled it
- The association between dietary acid load and endometriosis: a case-control study.BMC women's health · 2026Article
- Social determinants of health in medical education: insights from final-year students in a multicentre study in Italy.Updates in surgery · 2026Article
- Association of Dietary Acid Load with Metabolic Syndrome-Related Parameters Following Eating Habit Modification in Korean Adults.Nutrients · 2026Article
- Assessment of the acidifying potential of diet and sarcopenia in individuals 50 years of age or older: a cross-sectional study.BMC nutrition · 2026Article
- The association between dietary acid load and Kidney/Liver function in morbidly obese bariatric candidates.BMC nutrition · 2025Article
- Dietary acid load and mortality in the Japan Multi-Institutional Collaborative Cohort Study.Scientific reports · 2025Article
- Increased dietary acid load May elevate the risk of coronary artery disease severity: Findings from a cross-sectional study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Dietary acid load and the odds of knee osteoarthritis: a case-control study.Scientific reports · 2025Article
- The Effect of Dietary Acid Load on Cardiometabolic Risk, Psychological Resilience and Sleep Quality in Adolescents with ObesityJournal of clinical research in pediatric endocrinology · 2025Article
- The association between dietary acid load and odds of prostate cancer: a case-control study.Journal of health, population, and nutrition · 2025Article
- Article
- Association between dietary acid load and risk of metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes.Frontiers in nutrition · 2025Article
- Translational Algorithms for Technological Dietary Quality Assessment Integrating Nutrimetabolic Data with Machine Learning Methods.Nutrients · 2024Article
- Dietary acid load adopts the effect of ApoB ins/del genetic variant (rs11279109) on obesity trait, cardiovascular markers, lipid profile, and serum leptin level among patients with diabetes: a cross-sectional study.Scientific reports · 2024Article
- Assessing the role of dietary acid load in the development of hypertensive disorders during pregnancy: uncovering the association through prospective cohort analysis.Nutrition journal · 2024Article
- Dietary acid load in health and disease.Pflugers Archiv : European journal of physiology · 2024Review
- Evaluation of the relationship between dietary acid load and cardiovascular risk factors in patients with type 2 diabetes: a case-control study.Frontiers in nutrition · 2024Article
- Health Inequities in the USA: a Role for Dietary Acid Load? Results from the National Health and Nutrition Examination Surveys.Journal of racial and ethnic health disparities · 2023Article
- Benefits in routinely measured liver function tests following bariatric surgery: a retrospective cohort study.Journal of diabetes and metabolic disorders · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the current meta-analysis, we aimed to systematically review and summarize the eligible studies evaluating the association between dietary acid load in terms of potential renal acid load (PRAL) and net-endogenous acid production (NEAP) with anthropometric parameters and serum lipids in adult population.
methodsIn a systematic search from PubMed, Scopus, Web of Sciences and Cochrane electronic databases up to December 2018, relevant studies were included. Cross-sectional, case control or cohort studies evaluating the association between PRAL and NEAP with the mean values of body mass index (BMI), waist circumference (WC), low and high density lipoprotein cholesterol (LDL, HDL), triglyceride (TG), total cholesterol (TC) and the prevalence of obesity were included.
resultsAccording to our results, having higher dietary acid load content in terms of high PRAL scores was associated with higher triglyceride concentrations (weighted mean difference (WMD): 3.468; confidence interval (CI): -0.231, 7.166, P = 0.04) and higher obesity prevalence (30% and 27% in highest versus lowest categories). Accordingly, being in the highest category of NEAP was associated with higher prevalence of obesity (25% and 22% in highest versus lowest category). In subgroup analysis, higher PRAL scores was associated with higher BMI in women (WMD: 0.122; CI: -0.001, 0.245; P = 0.049) and higher NEAP in men (WMD: 0.890; CI: 0.430, 1.350; P < 0.001). There was no association between dietary acid load and other studied parameters.
conclusionsIn the current meta-analysis, high dietary acid load content was associated with higher serum triglyceride concentrations and higher obesity prevalence. Reducing dietary acid load content might be a useful preventive strategy against obesity and metabolic disorders.
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