Evidence map›Paper›PMID 31071096›Full record

ArticlePloS one2019

The effect of community dialogues and sensitization on patient reporting of adverse events in rural Uganda: Uncontrolled before-after study.

Helen Byomire Ndagije, Leonard Manirakiza, Dan Kajungu, Edward Galiwango, Donna Kusemererwa, Sten Olsson, Anne Spinewine, Niko Speybroeck

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Helen Byomire NdagijeNational Pharmacovigilance Centre, National Drug Authority, Kampala, Uganda.ORCID 0000-0001-5802-4791
Leonard ManirakizaNational Pharmacovigilance Centre, National Drug Authority, Kampala, Uganda.ORCID 0000-0001-7273-2866
Dan KajunguMakerere University Centre for Health and Population Research, Iganga, Uganda.
Edward GaliwangoMakerere University Centre for Health and Population Research, Iganga, Uganda.
Donna KusemererwaNational Pharmacovigilance Centre, National Drug Authority, Kampala, Uganda.
Sten OlssonSten Olsson Pharmacovigilance Consulting, Uppsala, Sweden.
Anne SpinewineInstitute of Health and Society (IRSS), Université Catholique de Louvain, Brussels, Belgium.
Niko SpeybroeckInstitute of Health and Society (IRSS), Université Catholique de Louvain, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients experiencing adverse drug events (ADE) in many developing countries are in the best position to report these events to the authorities but need to be empowered to do so. Systematic evaluation of community engagement and patient support especially in rural areas would provide evidence for a program to monitor potential harm from medicines. The aim of this study was to assess the effects of a community dialogue and sensitization (CDS) program on the knowledge, attitude and practises of community members for reporting ADE.

methodsThis an uncontrolled before-after study was conducted in two eastern Ugandan districts between September 2016 and August 2017.

resultsAfter implementation of the community dialogue and sensitization (CDS) program, there was an overall 20% (95% CI:16% to 25%) increase in knowledge about ADE in the community compared to before the program began. Awareness levels increased by 50% (95% CI: 37% to 63%) among those with little or no education and by41% (95% CI: 31% to 52%) among young people (15-24 years). Furthermore, 5% (95% CI: 3% to 7%) more respondents recognized the need for reporting ADEs compared to before the program. Finally, there was a significant increase of 115% (95% CI:137% to 217%) in respondent recognition and reporting of ADEs compared to the beginning of the CDS program. Overall, this community found the CDS program acceptable and proposed aspects that could be improved for future use.

conclusionOur evaluation showed that the CDS program increased knowledge and improved attitudes by catalyzing discussions among community members and healthcare professionals on health issues and monitoring safety of medicines compared to before the program. Successful implementation of the program depends on holistic health systems strengthening and adaptation to the community's way of life.

Indexed as

Public HealthRural PopulationSelf ReportAdverse Drug Reaction Reporting SystemsControlled Before-After StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansMalePatient Acceptance of Health CarePopulation SurveillanceUganda

Identifiers

PMID31071096
PMCPMC6508596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.