ReviewJournal of applied physiology (Bethesda, Md. : 1985)2019
Muscle thixotropy-where are we now?
Review in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Cross-bridge model for predicting muscle short-range stiffness during movement.PLoS computational biology · 2026Article
- Characteristics of Post-Exercise Lower Limb Muscle Tremor Among Speed Skaters.Sensors (Basel, Switzerland) · 2025Article
- Increased coactivation during clinical tests of spasticity is associated with increased coactivation during reactive standing balance control in cerebral palsy.Journal of neurophysiology · 2025Article
- Supine Bridge Exercise for Low Back Pain: A Fascial Approach for Movement Impairment Syndromes (Part II).Cureus · 2025Review
- A Comparative Study of Platysmal Myoneurectomy With Variations of Selective Neurectomies in Post-Facial Palsy Synkinesis.Microsurgery · 2025Article
- The effect of nordic walking with poles with an integrated resistance shock absorber on muscle stiffness and elasticity indicators in postmenopausal women.Frontiers in physiology · 2025Article
- Center of mass states render multijoint torques throughout standing balance recovery.Journal of neurophysiology · 2025Article
- Elite Tennis Players with a Weak Rotator Cuff: The Paradox of Infraspinatus Atrophy - A Clinical Commentary and Practical Approach.International journal of sports physical therapy · 2025Article
- Intrafusal cross-bridge dynamics shape history-dependent muscle spindle responses to stretch.Experimental physiology · 2024Article
- Article
- Identification of Neural and Non-Neural Origins of Joint Hyper-Resistance Based on a Novel Neuromechanical Model.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024Article
- History-dependent muscle resistance to stretch remains high after small, posturally relevant pre-movements.The Journal of experimental biology · 2023Article
- Another Way to Confuse Motor Control: Manual Technique Supposed to Shorten Muscle Spindles Reduces the Muscular Holding Stability in the Sense of Adaptive Force in Male Soccer Players.Brain sciences · 2023Article
- How to Confuse Motor Control: Passive Muscle Shortening after Contraction in Lengthened Position Reduces the Muscular Holding Stability in the Sense of Adaptive Force.Life (Basel, Switzerland) · 2023Article
- Acute effects of an isometric neck warm-up programme on neck performance characteristics and ultrasound-based morphology.Annals of medicine · 2023Article
- Influence of Spinal Movements Associated with Physical Evaluation on Muscle Mechanical Properties of the Lumbar Paraspinal in Subjects with Acute Low Back Pain.Diagnostics (Basel, Switzerland) · 2022Article
- Muscle Shear Elastic Modulus Provides an Indication of the Protection Conferred by the Repeated Bout Effect.Frontiers in physiology · 2022Article
- Bioprinted nanocomposite hydrogels: A proposed approach to functional restoration of skeletal muscle and vascular tissue following volumetric muscle loss.Current opinion in pharmacology · 2021Review
- Non-cross Bridge Viscoelastic Elements Contribute to Muscle Force and Work During Stretch-Shortening Cycles: Evidence From Whole Muscles and Permeabilized Fibers.Frontiers in physiology · 2021Article
- Individual differences in intrinsic ankle stiffness and their relationship to body sway and ankle torque.PloS one · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Relaxed skeletal muscle has an inbuilt resistance to movement. In particular, the resistance manifests itself as a substantial stiffness for small movements. The stiffness is impermanent, because it forms only when the muscle is stationary for some time and is reduced upon active or passive movement. Because the resistance to movement increases with time at rest and is reduced by movement, this behavior has become known as muscle thixotropy. In this short review, we describe the phenomenon of thixotropy and illustrate its significance in postural control with particular emphasis on human standing. We show how thixotropy came to be unambiguously associated with muscle mechanics and we review present knowledge of the molecular basis of thixotropic behavior. Specifically, we examine how recent knowledge about titin, and about the control of cross-bridge cycling, has impacted on the role of non-cross-bridge mechanisms and cross-bridge mechanisms in explaining thixotropy. We describe how thixotropic changes in muscle stiffness that occur during transitions from posture to movement can be tracked by analyzing physiological tremor. Finally, because skeletal muscle contains sensory receptors, and because some of these receptors are themselves thixotropic, we outline some of the consequences of muscle thixotropy for proprioception.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.