Evidence map›Paper›PMID 31070952›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

Impaired dynamic cerebral autoregulation in trained breath-hold divers.

M Erin Moir, Stephen A Klassen, Baraa K Al-Khazraji, Emilie Woehrle, Sydney O Smith, Brad J Matushewski, Duško Kozić, Željko Dujić, Otto F Barak, J Kevin Shoemaker

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In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Advances in breath-hold diving research: a state-of-the-art review.European journal of applied physiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

M Erin MoirSchool of Kinesiology, University of Western Ontario , London, Ontario , Canada.
Stephen A KlassenSchool of Kinesiology, University of Western Ontario , London, Ontario , Canada.
Baraa K Al-KhazrajiSchool of Kinesiology, University of Western Ontario , London, Ontario , Canada.
Emilie WoehrleSchool of Kinesiology, University of Western Ontario , London, Ontario , Canada.
Sydney O SmithSchool of Kinesiology, University of Western Ontario , London, Ontario , Canada.
Brad J MatushewskiSchool of Kinesiology, University of Western Ontario , London, Ontario , Canada.
Duško KozićFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Željko DujićDepartment of Physiology, University of Split School of Medicine , Split , Croatia.
Otto F BarakFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
J Kevin ShoemakerSchool of Kinesiology, University of Western Ontario , London, Ontario , Canada.
Western University · CAUniversity of Novi Sad · RSUniversity of Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breath-hold divers (BHD) experience repeated bouts of severe hypoxia and hypercapnia with large increases in blood pressure. However, the impact of long-term breath-hold diving on cerebrovascular control remains poorly understood. The ability of cerebral blood vessels to respond rapidly to changes in blood pressure represents the property of dynamic autoregulation. The current investigation tested the hypothesis that breath-hold diving impairs dynamic autoregulation to a transient hypotensive stimulus. Seventeen BHD (3 women, 11 ± 9 yr of diving) and 15 healthy controls (2 women) completed two or three repeated sit-to-stand trials during spontaneous breathing and poikilocapnic conditions. Heart rate (HR), finger arterial blood pressure (BP), and cerebral blood flow velocity (BFV) from the right middle cerebral artery were measured continuously with three-lead electrocardiography, finger photoplethysmography, and transcranial Doppler ultrasonography, respectively. End-tidal carbon dioxide partial pressure was measured with a gas analyzer. Offline, an index of cerebrovascular resistance (CVRi) was calculated as the quotient of mean BP and BFV. The rate of the drop in CVRi relative to the change in BP provided the rate of regulation [RoR; (∆CVRi/∆T)/∆BP]. The BHD demonstrated slower RoR than controls (

Indexed as

AdultApneaBlood Flow VelocityBlood PressureBrainBreath HoldingCarbon DioxideCerebrovascular CirculationDivingElectrocardiographyFemaleHeart RateHomeostasisHumansHypercapniaHypoxiaCarbon Dioxidebreath-hold diverscerebral autoregulationrate of regulationsit-to-standtranscranial Doppler ultrasonography

Identifiers

PMID31070952
PMCPMC6620660
OpenAlexW2944200577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.