Evidence map›Paper›PMID 31070054›Full record

ArticleEpigenomics2019

Commonly integrated epigenetic modifications of differentially expressed genes lead to adaptive resistance in cancer.

Abdullah Al Emran, Diego M Marzese, Dinoop R Menon, Heinz Hammerlindl, Farzana Ahmed, Erika Richtig, Pascal Duijf, Dave Sb Hoon, Helmut Schaider

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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  8. Research progress of omics technology in the field of tumor resistance: From singleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Abdullah Al EmranDermatology Research Centre, The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.
Diego M MarzeseDepartment of Translational Molecular Medicine, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.
Dinoop R MenonDepartment of Translational Molecular Medicine, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.
Heinz HammerlindlDermatology Research Centre, The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.
Farzana AhmedThe University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.
Erika RichtigDepartment of Dermatology, Medical University of Graz, Graz, Austria.
Pascal DuijfThe University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.
Dave Sb HoonCentenary Institute of Cancer Medicine & Cell Biology, University of Sydney, Camperdown, NSW, Australia.
Helmut SchaiderDermatology Research Centre, The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, QLD, Australia.
University of Queensland · AUSaint John's Health Center · USMedical University of Graz · ATTranslational Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell Line, TumorDNA MethylationDown-RegulationDrug Resistance, NeoplasmDrug ToleranceGene Expression ProfilingHistonesHumansInsulin-Like Growth Factor Binding Protein 5NeoplasmsPromoter Regions, GeneticSurvival AnalysisHistonesInsulin-Like Growth Factor Binding Protein 5adaptive resistancedifferentially expressed genesDNA methylationepigenetic remodelingIDTCinduced drug-tolerant cellLINE-1repressive histone marksviral mimicry

Identifiers

PMID31070054
PMCPMC6595545
OpenAlexW2943844564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.