Evidence map›Paper›PMID 31069861›Full record

ArticleMagnetic resonance in medicine2019

Accelerated whole-brain perfusion imaging using a simultaneous multislice spin-echo and gradient-echo sequence with joint virtual coil reconstruction.

Mary Kate Manhard, Berkin Bilgic, Congyu Liao, SoHyun Han, Thomas Witzel, Yi-Fen Yen, Kawin Setsompop

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Aberrant vascular architecture in the hippocampus correlates with tau burden in mild cognitive impairment and Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  4. Accelerated Simultaneous TTomography (Ann Arbor, Mich.) · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mary Kate ManhardAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.
Berkin BilgicAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.
Congyu LiaoAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.ORCID 0000-0003-2270-276X
SoHyun HanAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.
Thomas WitzelAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.
Yi-Fen YenAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.
Kawin SetsompopAthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.

Funding

MRI CORTICOGRAPHY: DEVELOPING NEXT GENERATION MICROSCALE HUMAN CORTEX MRI SCANNERU01EB025162 · NIBIB · UNIVERSITY OF CALIFORNIA BERKELEY · PI FEINBERG, DAVID ALAN, LIU, CHUNLEI · 2017 to 2021
$13.4M
Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Next generation in-vivo diffusion imaging at submillimeter resolutionR01MH116173 · NIMH · STANFORD UNIVERSITY · PI Yogesh Rathi, Kawin Setsompop · 2018 to 2026
$6.2M
fMRI Technologies for Imaging at the Limit of Biological Spatiotemporal Resolution: Administrative SupplementR01EB019437 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI POLIMENI, JONATHAN RIZZO, SETSOMPOP, KAWIN · 2015 to 2024
$5.5M
Rapid MRI acquisition for pediatric low-grade gliomasR01EB020613 · NIBIB · STANFORD UNIVERSITY · PI SETSOMPOP, KAWIN · 2016 to 2019
$2.5M
A Storage Area Network for Structural and Functional Image AnalysisS10RR023401 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2009 to 2009
$2.0M
SILICON GRAPHICS PRISM EXTREME 128P/1TBS10RR023043 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$1.5M
A 3.0 Tesla MRI System in a Neuroscience ICUS10RR019254 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2004 to 2004
$500k
Computeserver Structural &Functional Image AnalysisS10RR019307 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2004 to 2004
$496k
Enhanced spatio-temporal quantitative techniques for assessing tumor dynamics and vessel architecture using perfusion MRIF32EB026304 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI MANHARD, MARY · 2018 to 2019
$124k
NCRR NIH HHS S10 RR019254NCRR NIH HHS S10 RR019307NCRR NIH HHS S10 RR023043NCRR NIH HHS S10 RR023401NIBIB NIH HHS F32 EB026304NIBIB NIH HHS P41 EB015896NIBIB NIH HHS R01 EB019437NIBIB NIH HHS R01 EB020613NIBIB NIH HHS U01 EB025162NIMH NIH HHS R01 MH116173
6 · The paper itself

Abstract

purposeDynamic susceptibility contrast imaging requires high temporal sampling, which poses limits on achievable spatial coverage and resolution. Additionally, more encoding-intensive multi-echo acquisitions for quantitative imaging are desired to mitigate contrast leakage effects, which further limits spatial encoding. We present an accelerated sequence that provides whole-brain coverage at an improved spatio-temporal resolution, to allow for dynamic quantitative R

methodsA multi-echo spin and gradient-echo sequence was implemented with simultaneous multislice acquisition. Complementary k-space sampling between repetitions and joint virtual coil reconstruction were used along with a dynamic phase-matching technique to achieve high-quality reconstruction at 9-fold acceleration, which enabled 2 × 2 × 5 mm whole-brain imaging at TR of 1.5 to 1.7 seconds. The multi-echo images from this sequence were fit to achieve quantitative R

resultsImages reconstructed using joint virtual coil show improved image quality and g-factor compared with conventional reconstruction methods, resulting in improved quantitative maps with a 9-fold acceleration factor and whole-brain coverage during the dynamic perfusion acquisition.

conclusionThe method presented shows the advantage of using a joint virtual coil-GRAPPA reconstruction to allow for high acceleration factors while maintaining reliable image quality for quantitative perfusion mapping, with the potential to improve tumor diagnostics and monitoring.

Indexed as

BrainCerebrovascular CirculationHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPerfusion Imagingdynamic susceptibility contrastjoint reconstructionparallel imagingperfusionsimultaneous multislicevirtual coil

Identifiers

PMID31069861
PMCPMC6692914

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.