Evidence map›Paper›PMID 31069713›Full record

ArticleBehavior research methods2019

A Bayesian nonlinear mixed-effects location scale model for learning.

Donald R Williams, Daniel R Zimprich, Philippe Rast

Abstract read
In one paragraph

Article in Behavior research methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Personality trait and state associations with cognitive functioning and variability in middle-aged and older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  3. Article
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  6. Demographic factors associated with within-individual variability of lung function for adults with cystic fibrosis: A UK registry study.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2024
    Article
  7. Article
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  14. Bayesian Multivariate Mixed-Effects Location Scale Modeling of Longitudinal Relations Among Affective Traits, States, and Physical Activity.European journal of psychological assessment : official organ of the European Association of Psychological Assessment · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Donald R WilliamsUniversity of California, Davis, Davis, CA, USA.
Daniel R ZimprichUlm University, Ulm, Germany.
Philippe RastUniversity of California, Davis, Davis, CA, USA. prast@ucdavis.edu.ORCID http://orcid.org/0000-0003-3630-6629

Funding

A Multi-Study Replication of the Predictive Value of Intra-Individual Variabilityon Long-Term Changes in Cognition, Health and AffectR01AG050720 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RAST, PHILIPPE · 2016 to 2018
$741k
NIA NIH HHS R01 AG050720
6 · The paper itself

Abstract

We present a Bayesian nonlinear mixed-effects location scale model (NL-MELSM). The NL-MELSM allows for fitting nonlinear functions to the location, or individual means, and the scale, or within-person variance. Specifically, in the context of learning, this model allows the within-person variance to follow a nonlinear trajectory, where it can be determined whether variability reduces during learning. It incorporates a sub-model that can predict nonlinear parameters for both the location and scale. This specification estimates random effects for all nonlinear location and scale parameters that are drawn from a common multivariate distribution. This allows estimation of covariances among the random effects, within and across the location and the scale. These covariances offer new insights into the interplay between individual mean structures and intra-individual variability in nonlinear parameters. We take a fully Bayesian approach, not only for ease of estimation but also for inference because it provides the necessary and consistent information for use in psychological applications, such as model selection and hypothesis testing. To illustrate the model, we use data from 333 individuals, consisting of three age groups, who participated in five learning trials that assessed verbal memory. In an exploratory context, we demonstrate that fitting a nonlinear function to the within-person variance, and allowing for individual variation therein, improves predictive accuracy compared to customary modeling techniques (e.g., assuming constant variance). We conclude by discussing the usefulness, limitations, and future directions of the NL-MELSM.

Indexed as

Bayes TheoremAgedFemaleHumansMaleNonlinear DynamicsResearch DesignYoung AdultBayesian inferenceIntra-individual variabilityNonlinear mixed-effects location scale modelVerbal learning

Identifiers

PMID31069713
PMCPMC6800615

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.