Evidence map›Paper›PMID 31069698›Full record

ArticleJournal of the American Society for Mass Spectrometry2019

Systematic Ion Source Parameter Assessment by Automated Determination of the Distribution of Ion Acceptance (DIA) Using APLI.

Walter Wißdorf, Matthias Lorenz, Klaus Brockmann, Thorsten Benter

Abstract read
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In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. A First Principle Model of Differential Ion Mobility: the Effect of Ion-Solvent Clustering.Journal of the American Society for Mass Spectrometry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Walter WißdorfDepartment of Physical and Theoretical Chemistry, University of Wuppertal, Gauss Str. 20, 42119, Wuppertal, Germany. wissdorf@uni-wuppertal.de.ORCID http://orcid.org/0000-0002-4987-5807
Matthias LorenzDepartment of Physical and Theoretical Chemistry, University of Wuppertal, Gauss Str. 20, 42119, Wuppertal, Germany.
Klaus BrockmannDepartment of Physical and Theoretical Chemistry, University of Wuppertal, Gauss Str. 20, 42119, Wuppertal, Germany.
Thorsten BenterDepartment of Physical and Theoretical Chemistry, University of Wuppertal, Gauss Str. 20, 42119, Wuppertal, Germany.
University of Wuppertal · DEOak Ridge National Laboratory · US

Funding

Deutsche Forschungsgemeinschaft (DE) BE BE2124/6-1
6 · The paper itself

Abstract

The determination of the spatially resolved ion signal with atmospheric pressure laser ionization (APLI), which was introduced as distribution of ion acceptance (DIA), serves as a valuable tool for the understanding of complex and highly dynamical conditions in modern atmospheric pressure (AP) ion sources. DIA provides information about fluid dynamics, ion transport, and ion transformation processes in such sources and is an ideal basis for the validation of numerical models of the dynamics in the ion source enclosure.We present a fully automated setup for DIA measurements, which enabled us to acquire a comprehensive dataset of over 700 individual DIA measurements in a commercial AP ion source (Bruker Multi Purpose Ion Source, MPIS). Ion source parameters as voltages, gas heater temperatures and gas flows, were varied, and the effect of those parameters on the DIA of a chemically inert analyte, pyrene, was systematically investigated. It is shown that the response of the DIA is nonlinear and that gas dynamics largely dominates the ion transport in the ion source. Particularly, the position of the heated nebulizer, which is used to introduce one of two gas flows and the analyte into the ion source chamber, had a profound effect on the DIA. This suggests that the gas dynamics in the source switches between different states. The now available comprehensive DIA dataset reveals such critical effects and will guide further numerical modeling efforts to understand the details of the dynamics of ions in the source chamber. Graphical Abstract.

Indexed as

APIAPLIAtmospheric pressure ionizationGas flowsIon source parametersIon sourcesLaser ionizationSpatially resolved ionization

Identifiers

PMID31069698
OpenAlexW2943916389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.