Evidence map›Paper›PMID 31069636›Full record

ArticleGeroScience2019

Do cytomegalovirus-specific memory T cells interfere with new immune responses in lymphoid tissues?

Mladen Jergović, Jennifer L Uhrlaub, Nico A Contreras, Janko Nikolich-Žugich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GeroScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Immune surveillance of cytomegalovirus in tissues.Cellular & molecular immunology · 2024
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mladen JergovićDepartment of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine-Tucson, P.O. Box 221245, 1501 N Campbell Ave, Tucson, AZ, 85724, USA.
Jennifer L UhrlaubDepartment of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine-Tucson, P.O. Box 221245, 1501 N Campbell Ave, Tucson, AZ, 85724, USA.
Nico A ContrerasDepartment of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine-Tucson, P.O. Box 221245, 1501 N Campbell Ave, Tucson, AZ, 85724, USA.
Janko Nikolich-ŽugichDepartment of Immunobiology and the University of Arizona Center on Aging, University of Arizona College of Medicine-Tucson, P.O. Box 221245, 1501 N Campbell Ave, Tucson, AZ, 85724, USA. nikolich@email.arizona.edu.

Funding

T Cell Homeostasis and Function in Immune SenescenceR37AG020719 · NIA · UNIVERSITY OF ARIZONA · PI JANKO Z. NIKOLICH · 2018 to 2026
$4.2M
T Cell Homeostasis and Function in Immune SenescenceR01AG020719 · NIA · UNIVERSITY OF ARIZONA · PI NIKOLICH, JANKO Z. · 2001 to 2012
$3.1M
Research Supplement to Impact on CMV Upon T-Cell Aging and Immune DefenseR01AG048021 · NIA · UNIVERSITY OF ARIZONA · PI NIKOLICH, JANKO Z. · 2014 to 2018
$2.6M
NIA NIH HHS AG048021NIA NIH HHS R01 AG020719NIA NIH HHS R01 AG048021NIA NIH HHS R37 AG020719
6 · The paper itself

Abstract

In both mice and humans, the CD8 T cell compartment is expanded with age in the presence of a cytomegalovirus (CMV) infection due to an absolute increase in the CD8+ T cell effector memory (T

Indexed as

Immunologic MemoryAdoptive TransferAnimalsCD8-Positive T-LymphocytesCytomegalovirusCytomegalovirus InfectionsDisease Models, AnimalHumansLymphoid TissueMaleMiceMice, Inbred C57BLRandom AllocationSensitivity and SpecificityStatistics, NonparametricCytomegalovirus-specific memory T cellsLymphoid tissuesWest Nile virus

Identifiers

PMID31069636
PMCPMC6544713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.