Evidence map›Paper›PMID 31069583›Full record

ArticleJournal of abnormal child psychology2019

Developmental Trajectories of Anxiety and Depression Symptoms from Early to Middle Childhood: a Population-Based Cohort Study in the Netherlands.

Jasmijn M de Lijster, Michiel A van den Dries, Jan van der Ende, Elisabeth M W J Utens, Vincent W Jaddoe, Gwendolyn C Dieleman, Manon H J Hillegers, Henning Tiemeier, Jeroen S Legerstee

Abstract read
In one paragraph

Article in Journal of abnormal child psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  5. Mental health trajectory groups: Family income, neighborhood disadvantage, and role of the school environment.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
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  16. Preschool Mood Disorders: A Review of the Literature from 2017 to 2024.Child and adolescent psychiatric clinics of North America · 2025
    Review
  17. The impact of universal mental health screening on stigma in primary schools.Child and adolescent psychiatry and mental health · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jasmijn M de LijsterDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands.
Michiel A van den DriesDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands.
Jan van der EndeDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands.
Elisabeth M W J UtensDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands.
Vincent W JaddoeThe Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands.
Gwendolyn C DielemanDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands.
Manon H J HillegersDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands.
Henning TiemeierDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands.
Jeroen S LegersteeDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, P.O. Box 2060, Wytemaweg 80, 3000, CB, Rotterdam, the Netherlands. j.s.legerstee@erasmusmc.nl.

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek 024.001.003Nederlandse Organisatie voor Wetenschappelijk Onderzoek/ZonMW (NL) 016.VICI.170.200Sophia Children's Hospital Research Foundation (NL) S13-11Stichting Coolsingel 251
6 · The paper itself

Abstract

Developmental patterns of anxiety and depression symptoms in early childhood have previously been related to anxiety and mood disorders in middle childhood. In the current study, trajectories of anxiety and depression symptoms (1.5-10 years) were related to children's broader psychosocial and school-related functioning at 10 years. We included a population-based sample of 7499 children, for whom primary caregivers reported anxiety and depression symptoms on the Child Behavior Checklist, at children's ages of 1.5, 3, 6, and 10. Growth Mixture Modeling identified four distinct, gender-invariant, trajectories of anxiety and depression symptoms: low (82.4%), increasing (7.4%), decreasing (6.0%), and increasing symptoms up to age 6 followed by a decrease to age 10 (preschool-limited, 4.2%). Children with a non-Dutch ethnicity had lower odds to be in the increasing trajectory and higher odds to be in the decreasing and pre-school limited trajectory. Also, low maternal education predicted the decreasing and pre-school limited trajectory. Higher levels of psychopathology during pregnancy for both mothers and fathers predicted the increasing, decreasing, and preschool-limited trajectory, compared to the low trajectory. At age 10, children in the increasing and preschool-limited trajectory had diminished psychosocial outcomes (friendship-quality and self-esteem) and worse school-related outcomes (school performance and school problems). This study adds to current knowledge by demonstrating that developmental patterns of anxiety and depression symptoms in early childhood are related to broader negative outcomes in middle childhood. Child and family factors could guide monitoring of anxiety and depression symptoms in the general population and provide targets for prevention programs.

Indexed as

AnxietyChild DevelopmentDepressionChildChild, PreschoolCohort StudiesFemaleHumansInfantMaleNetherlandsAnxiety and depression symptomsDevelopmental trajectoriesEarly childhoodGrowth mixture modelingPsychosocial outcomesSchool outcomes

Identifiers

PMID31069583
PMCPMC6805800

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.