Evidence map›Paper›PMID 31069504›Full record

ArticleJournal of mathematical biology2019

Sample path properties of the average generation of a Bellman-Harris process.

Gianfelice Meli, Tom S Weber, Ken R Duffy

Abstract read
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In one paragraph

Article in Journal of mathematical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Why are cell populations maintained via multiple compartments?Journal of the Royal Society, Interface · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gianfelice MeliHamilton Institute, Maynooth University, Co. Kildare, Ireland.
Tom S WeberThe Walter and Eliza Hall Institute of Medical Research, The University of Melbourne, Parkville, Australia.
Ken R DuffyHamilton Institute, Maynooth University, Co. Kildare, Ireland. ken.duffy@mu.ie.ORCID 0000-0001-5587-9356

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivated by a recently proposed design for a DNA coded randomised algorithm that enables inference of the average generation of a collection of cells descendent from a common progenitor, here we establish strong convergence properties for the average generation of a super-critical Bellman-Harris process. We further extend those results to a two-type Bellman-Harris process where one type can give rise to the other, but not vice versa. These results further affirm the estimation method's potential utility by establishing its long run accuracy on individual sample-paths, and significantly expanding its remit to encompass cellular development that gives rise to differentiated offspring with distinct population dynamics.

Indexed as

DNA ReplicationModels, GeneticAlgorithmsCell Culture TechniquesCell DeathCell DifferentiationCell ProliferationComputer SimulationIntravital MicroscopyTelomere HomeostasisTime-Lapse ImagingAverage generation inferenceAverage tree depth inferenceBellman–Harris processDNA coded algorithmSample-path propertiesTwo-type process

Identifiers

PMID31069504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.