ArticleNucleic acids research2019
MISIM v2.0: a web server for inferring microRNA functional similarity based on microRNA-disease associations.
Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer's disease by meta-analysis and adaptive boosting ensemble learning.Alzheimer's research & therapy · 2021Pooled it
- From biogenesis to deep modeling: a holistic review of miRNA-disease prediction computational methods with experimental comparison.Briefings in bioinformatics · 2026Review
- GONNMDA: A Ordered Message Passing GNN Approach for miRNA-Disease Association Prediction.Genes · 2025Article
- SPLHRNMTF: robust orthogonal non-negative matrix tri-factorization with self-paced learning and dual hypergraph regularization for predicting miRNA-disease associations.BMC genomics · 2024Article
- miRNAs in Heart Development and Disease.International journal of molecular sciences · 2024Review
- MHIF-MSEA: a novel model of miRNA set enrichment analysis based on multi-source heterogeneous information fusion.Frontiers in genetics · 2024Article
- Mesenchymal stem cell-derived extracellular vesicles prevent the formation of pulmonary arterial hypertension through a microRNA-200b-dependent mechanism.Respiratory research · 2023Article
- Article
- BioSeq-Diabolo: Biological sequence similarity analysis using Diabolo.PLoS computational biology · 2023Article
- TLSEA: a tool for lncRNA set enrichment analysis based on multi-source heterogeneous information fusion.Frontiers in genetics · 2023Article
- Identifying the potential transcriptional regulatory network in Hirschsprung disease by integrated analysis of microarray datasets.World journal of pediatric surgery · 2023Article
- Immune cell-derived extracellular vesicular microRNAs induce pancreatic beta cell apoptosis.Heliyon · 2022Article
- iSnoDi-LSGT: identifying snoRNA-disease associations based on local similarity constraints and global topological constraints.RNA (New York, N.Y.) · 2022Article
- MIMRDA: A Method Incorporating the miRNA and mRNA Expression Profiles for Predicting miRNA-Disease Associations to Identify Key miRNAs (microRNAs).Frontiers in genetics · 2022Article
- Drug Repositioning with GraphSAGE and Clustering Constraints Based on Drug and Disease Networks.Frontiers in pharmacology · 2022Article
- Prediction of potential small molecule-miRNA associations based on heterogeneous network representation learning.Frontiers in genetics · 2022Article
- Bipartite graph-based collaborative matrix factorization method for predicting miRNA-disease associations.BMC bioinformatics · 2021Article
- Human microRNA similarity in breast cancer.Bioscience reports · 2021Article
- MSCFS: inferring circRNA functional similarity based on multiple data sources.BMC bioinformatics · 2021Article
- Multiplex-Heterogeneous Network-Based Capturing Potential SNP "Switches" of Pathways Associating With Diverse Disease Characteristics of Asthma.Frontiers in cell and developmental biology · 2021Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are one class of important small non-coding RNA molecules and play critical roles in health and disease. Therefore, it is important and necessary to evaluate the functional relationship of miRNAs and then predict novel miRNA-disease associations. For this purpose, here we developed the updated web server MISIM (miRNA similarity) v2.0. Besides a 3-fold increase in data content compared with MISIM v1.0, MISIM v2.0 improved the original MISIM algorithm by implementing both positive and negative miRNA-disease associations. That is, the MISIM v2.0 scores could be positive or negative, whereas MISIM v1.0 only produced positive scores. Moreover, MISIM v2.0 achieved an algorithm for novel miRNA-disease prediction based on MISIM v2.0 scores. Finally, MISIM v2.0 provided network visualization and functional enrichment analysis for functionally paired miRNAs. The MISIM v2.0 web server is freely accessible at http://www.lirmed.com/misim/.
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