Evidence map›Paper›PMID 31069269›Full record

ArticleCommunications biology2019

Cell type phylogenetics informs the evolutionary origin of echinoderm larval skeletogenic cell identity.

Eric M Erkenbrack, Jeffrey R Thompson

Abstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. A novel regulatory gene promotes novel cell fate by suppressing ancestral fate in the sea anemoneProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eric M Erkenbrack1Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06511 USA.ORCID 0000-0001-9375-3279
Jeffrey R Thompson3Department of Geosciences, Baylor University, Waco, TX 76706 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The multiplicity of cell types comprising multicellular organisms begs the question as to how cell type identities evolve over time. Cell type phylogenetics informs this question by comparing gene expression of homologous cell types in distantly related taxa. We employ this approach to inform the identity of larval skeletogenic cells of echinoderms, a clade for which there are phylogenetically diverse datasets of spatial gene expression patterns. We determined ancestral spatial expression patterns of

Indexed as

Gene Regulatory NetworksPhylogenyAnimalsAnimal ShellsBayes TheoremBiological EvolutionEchinodermataEmbryo, NonmammalianExtinction, BiologicalGene Expression Regulation, DevelopmentalLarvaMesodermStem CellsEvolutionary developmental biologyPhylogenetics

Identifiers

PMID31069269
PMCPMC6499829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.