Evidence map›Paper›PMID 31069223›Full record

ArticleFrontiers in cell and developmental biology2019

Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord.

Craig M Nelson, Vanda A Lennon, Han Lee, Randall G Krug, Aichurok Kamalova, Nicolas N Madigan, Karl J Clark, Anthony J Windebank, John R Henley

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Inflammation induces zebrafish regeneration.Neural regeneration research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Craig M NelsonDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Vanda A LennonDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States.
Han LeeDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States.
Randall G KrugDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States.
Aichurok KamalovaDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Nicolas N MadiganDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
Karl J ClarkDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States.
Anthony J WindebankDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
John R HenleyDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic in Arizona · USWinnMed · USMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following injury, the mammalian spinal cord forms a glial scar and fails to regenerate. In contrast, vertebrate fish spinal cord tissue regenerates significantly to restore function. Cord transection in zebrafish (

Indexed as

ependymal gliaglucocorticoid signalingneural regenerationNr3c1spinal cord injury

Identifiers

PMID31069223
PMCPMC6491705
OpenAlexW2940909921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.