Evidence map›Paper›PMID 31069187›Full record

ArticleSouth Asian journal of cancer

Efficacy of preoperative chemoradiotherapy in downstaging rectal cancer and its impact on the long-term outcome.

Janaki Gururajachar Manur, Rahil Bharatbhai Patel, Sathish Chandramouli

Abstract read
In one paragraph

Article in South Asian journal of cancer. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Janaki Gururajachar ManurDepartment of Radiotherapy, M. S. Ramaiah Medical College, Bengaluru, Karnataka, India.
Rahil Bharatbhai PatelDepartment of Radiotherapy, M. S. Ramaiah Medical College, Bengaluru, Karnataka, India.
Sathish ChandramouliDepartment of Surgical Oncology, M. S. Ramaiah Medical College, Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionResponse to preoperative chemoradiation (PRTCT) for rectal cancer predicts the long-term outcome. CONTEXT: Tertiary care hospital.

aimsThe aim is to study the factors affecting the response to chemoradiation. SETTINGS AND

designRetrospective. MATERIALS AND

methodsTwenty-three patients of rectal cancer undergoing PRTCT followed by surgery and adjuvant chemotherapy were followed up for 20-56 months. Postoperative response, tumor downstaging and nodal downstaging were correlated with the disease status.

resultsTumor downstaging was seen in 11 (50%) and nodal downstaging in 12 (63.15%) patients. Nodal downstaging was statistically significant with

conclusionMost patients of rectal cancer show PR to PRTCT, and the benefit is more for node-positive patients. Nodal PCR is associated with a higher chance of long-term disease control.

Indexed as

Downstaginglong-term outcomepreoperative radiationrectal cancer

Identifiers

PMID31069187
PMCPMC6498706

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LicenceCC BY-NC-SA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.