ReviewF1000Research2019
Recent advances in understanding anorexia nervosa.
Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Brain networks in eating disorders: a systematic review of graph theory studies.Eating and weight disorders : EWD · 2022Pooled it
- Moving towards specificity: A systematic review of cue features associated with reward and punishment in anorexia nervosa.Clinical psychology review · 2020Pooled it
- Anorexia nervosa: 150 years of critical theory.Journal of eating disorders · 2026Review
- Endogenous opioid receptors and the feast or famine of maladaptive feeding.Nature communications · 2025Review
- Interaction between emotion lability, emotion regulation and structural brain abnormalities in patients with anorexia nervosa and borderline personality disorder.Frontiers in neuroscience · 2025Article
- Anorexia Nervosa Across the Lifespan: A Review of Recent Literature.Focus (American Psychiatric Publishing) · 2024Review
- Therapeutic ketogenic diet as treatment for anorexia nervosa.Frontiers in nutrition · 2024Review
- Habits and Persistent Food Restriction in Patients with Anorexia Nervosa: A Scoping Review.Behavioral sciences (Basel, Switzerland) · 2023Article
- The relationship between cannabis and anorexia nervosa: a scoping review.Journal of eating disorders · 2023Article
- Induction of Activity-Regulated Cytoskeleton-Associated Protein and c-Fos Expression in an Animal Model of Anorexia Nervosa.Nutrients · 2023Article
- Similarities and differences regarding acute anorexia nervosa and semi-starvation: does behavioral thermoregulation play a central role?Frontiers in behavioral neuroscience · 2023Article
- Emergency Department Utilization by Patients With Eating Disorders: A National Population-Based Study.Cureus · 2022Article
- Genetics and neurobiology of eating disorders.Nature neuroscience · 2022Review
- Subjective Experience of Antidepressant Prescription Among Adolescents With Anorexia Nervosa.Frontiers in psychiatry · 2022Article
- Temperament-based treatment for young adults with eating disorders: acceptability and initial efficacy of an intensive, multi-family, parent-involved treatment.Journal of eating disorders · 2021Article
- Cortical thinning and associated connectivity changes in patients with anorexia nervosa.Translational psychiatry · 2021Article
- Altered habenula to locus coeruleus functional connectivity in past anorexia nervosa suggests correlation with suicidality: a pilot study.Eating and weight disorders : EWD · 2020Article
- A virtual issue highlighting animal studies of eating disorders as valuable tools for examining neurobiological underpinnings and treatment of eating disorders.The International journal of eating disorders · 2020Article
- Functional Connectivity Patterns and the Role of 5-HTTLPR Polymorphism on Network Architecture in Female Patients With Anorexia Nervosa.Frontiers in neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Anorexia nervosa is a complex psychiatric illness associated with food restriction and high mortality. Recent brain research in adolescents and adults with anorexia nervosa has used larger sample sizes compared with earlier studies and tasks that test specific brain circuits. Those studies have produced more robust results and advanced our knowledge of underlying biological mechanisms that may contribute to the development and maintenance of anorexia nervosa. It is now recognized that malnutrition and dehydration lead to dynamic changes in brain structure across the brain, which normalize with weight restoration. Some structural alterations could be trait factors but require replication. Functional brain imaging and behavioral studies have implicated learning-related brain circuits that may contribute to food restriction in anorexia nervosa. Most notably, those circuits involve striatal, insular, and frontal cortical regions that drive learning from reward and punishment, as well as habit learning. Disturbances in those circuits may lead to a vicious cycle that hampers recovery. Other studies have started to explore the neurobiology of interoception or social interaction and whether the connectivity between brain regions is altered in anorexia nervosa. All together, these studies build upon earlier research that indicated neurotransmitter abnormalities in anorexia nervosa and help us develop models of a distinct neurobiology that underlies anorexia nervosa.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.