ArticleAddiction & health2018
Cerebrovascular Reactivity and Carotid Intima-Media Thickness in Opium Dependents: A Case-Control Study.
Article in Addiction & health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Investigating the Relationship between Carotid Intima-Media Thickness (CIMT), Opium Addiction, and Components of the Metabolic Syndrome.Addiction & health · 2023Article
- Cross-sectional study of passive opiate smoking in relation to stroke and some of stroke attributable risk factors in women.Scientific reports · 2022Article
- Comparison of Brain Magnetic Resonance Imaging Lesions in Opium Addict and Non-addict Patients with Thrombotic Stroke: A Case-Control Study.Addiction & health · 2021Article
- Opium and cardiovascular health: A devil or an angel?Indian heart journalReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundThere is still no consensus among researchers on the impact of opium dependency on cerebrovascular stenosis. Some studies suggest that opium may be a risk factor for ischemic stroke. This study compared carotid intima-media thickness (CIMT) and cerebrovascular reactivity between opium-dependent and healthy people.
methodsThis case-control study was done among opium addicts at Shafa hospital in Kerman, Iran, in year 2018. People with systemic disease or who took any medicine were excluded from our study. The control group were selected from healthy non-addicted volunteers. The control group was matched in age and sex with the case group. Cerebrovascular reactivity of middle cranial artery and intima-media thickness of carotid artery were measured for all in both groups. The results were analyzed using chi-square, independent samples t, and logistic regression tests.
findings47 opium addicts and 47 healthy people entered this study. 88% of them were men and 12% were women. 68.1% of the case group and 31.9% of the control group were cigarette smokers; this difference was statistically significant. Comparison of cerebrovascular reactivity and CIMT between the two groups was statistically significant (P < 0.001). This relationship remained significant for the CIMT after removing confounding factors (P = 0.018).
conclusionOverall, our findings show that opium dependency affects the carotid intima-media thickness as an indicator of cerebral atherosclerosis.
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