Evidence map›Paper›PMID 31068976›Full record

ReviewChinese medicine2019

Review of traditional uses, botany, chemistry, pharmacology, pharmacokinetics, and toxicology of Radix Cyathulae.

Yongliang Huang, Shanshan Wang, Li Liu, Wei Peng, Jiaolong Wang, Ying Song, Qianghua Yuan, Xing Yuan, Chunjie Wu

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Chinese medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Effects and molecular mechanisms ofFrontiers in pharmacology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yongliang Huang *1Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072 China.
Shanshan Wang *2Chengdu University of Traditional Chinese Medicine, Chengdu, 610075 China.
Li Liu1Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072 China.
Wei Peng2Chengdu University of Traditional Chinese Medicine, Chengdu, 610075 China.
Jiaolong Wang2Chengdu University of Traditional Chinese Medicine, Chengdu, 610075 China.
Ying Song1Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072 China.
Qianghua Yuan1Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072 China.
Xing Yuan2Chengdu University of Traditional Chinese Medicine, Chengdu, 610075 China.
Chunjie Wu2Chengdu University of Traditional Chinese Medicine, Chengdu, 610075 China.
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyathulae Radix (CR), also known as "Chuanniux" is a well-known traditional Chinese herbal medicine that has been used in China for thousands of years. The present work reviewed advances in traditional uses, origin, chemical constituents, pharmacology, pharmacokinetics, and toxicity studies of CR. This work aims to provide more up-to-date references for modern study and application of this plant. Furthermore, the possible trends and perspectives for future research of this plant are also discussed. In China, the roots of CR have been widely used in clinical practice to treat orthopedic, gynecological, and urologic diseases. Currently, over 59 compounds have been isolated and identified from CR, including alkaloids and flavonoids. The extracts and compounds from CR have many pharmacological activities both in vivo and in vitro. They provide beneficial effects on the hematological system and anti-inflammatory properties. However, few studies have investigated the pharmacokinetics and toxicity of CR. Further studies should be undertaken to investigate the clinical effects, toxic constituents, and pharmacokinetics of CR; perform quality evaluation; and establish quality criteria for processed

Indexed as

Cyathulae RadixOriginPharmacokineticsPharmacologyPhytochemistryToxicologyTraditional usages

Identifiers

PMID31068976
PMCPMC6492438
OpenAlexW2947328051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.