Evidence map›Paper›PMID 31068966›Full record

ArticleFrontiers in genetics2019

P-TEFb Regulates Transcriptional Activation in Non-coding RNA Genes.

Heeyoun Bunch, Hyeseung Choe, Jongbum Kim, Doo Sin Jo, Soyeon Jeon, Sanghwa Lee, Dong-Hyung Cho, Keunsoo Kang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Role of Heat Shock Factors in Stress-Induced Transcription: An Update.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Long non-coding RNA NEAT1-centric gene regulation.Cellular and molecular life sciences : CMLS · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Heeyoun BunchDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, South Korea.
Hyeseung ChoeDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, South Korea.
Jongbum KimDepartment of Transcriptome & Epigenome, Macrogen Incorporated, Seoul, South Korea.
Doo Sin JoInstitute of Life Science and Biotechnology, College of Natural Science, Kyungpook National University, Daegu, South Korea.
Soyeon JeonDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, South Korea.
Sanghwa LeeDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, South Korea.
Dong-Hyung ChoDepartment of Life Science, College of Natural Science, Kyungpook National University, Daegu, South Korea.
Keunsoo KangDepartment of Microbiology, College of Natural Sciences, Dankook University, Cheonan, South Korea.
Kyungpook National University · KRDankook University · KRMacrogen (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many non-coding RNAs (ncRNAs) serve as regulatory molecules in various physiological pathways, including gene expression in mammalian cells. Distinct from protein-coding RNA expression, ncRNA expression is regulated solely by transcription and RNA processing/stability. It is thus important to understand transcriptional regulation in ncRNA genes but is yet to be known completely. Previously, we identified that a subset of mammalian ncRNA genes is transcriptionally regulated by RNA polymerase II (Pol II) promoter-proximal pausing and in a tissue-specific manner. In this study, human ncRNA genes that are expressed in the early G

Indexed as

gene expression regulationnon-coding RNAP-TEFbRNA polymerase II promoter-proximal pausingtranscriptional elongation

Identifiers

PMID31068966
PMCPMC6491683
OpenAlexW2940721170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.