ArticleFrontiers in immunology2019
CD4+Foxp3+T Regulatory Cells Promote Transplantation Tolerance by Modulating Effector CD4+ T Cells in a Neuropilin-1-Dependent Manner.
Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- TGF-β-induced Tregs release extracellular vesicles that modulate CD4+ T-cell proliferation and phenotype in a Nrp1-dependent manner.ImmunoHorizons · 2026Article
- CD4+FoxP3+ T regulatory cells subsets release small extracellular vesicles containing cell death-related proteins as potential mechanism of T cell suppression.Frontiers in immunology · 2026Article
- Induced Treg-Derived Extracellular Vesicles Suppress CD4Journal of extracellular vesicles · 2025Article
- Neuropilin-1: A Multifaceted Target for Cancer Therapy.Current oncology (Toronto, Ont.) · 2025Review
- PD-L1 restrains PD-1Cell reports · 2024Article
- Article
- Single-cell analysis of immune cells on gingiva-derived mesenchymal stem cells in experimental autoimmune uveitis.iScience · 2023Article
- Treatment with an antigen-specific dual microparticle system reverses advanced multiple sclerosis in mice.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation.Journal of extracellular vesicles · 2022Article
- Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis.Science immunology · 2022Article
- FK506 and Lactobacillus acidophilus ameliorate acute graft-versus-host disease by modulating the T helper 17/regulatory T-cell balance.Journal of translational medicine · 2022Article
- The contribution of neuropilin-1 in the stability of CD4Immunity, inflammation and disease · 2022Article
- Bone Mesenchymal Stem Cell-Derived Exosome-Enclosed miR-181a Induces CD4Journal of oncology · 2022Article
- CD49b Targeting Inhibits Tumor Growth and Boosts Anti-tumor Immunity.Frontiers in oncology · 2022Article
- Neuropilin-1 Identifies a New Subpopulation of TGF-β-Induced Foxp3Frontiers in immunology · 2022Article
- Bcl10 is required for the development and suppressive function of Foxp3Cellular & molecular immunology · 2021Article
- Role of NRP1 in Bladder Cancer Pathogenesis and Progression.Frontiers in oncology · 2021Article
- Neuropilins, as Relevant Oncology Target: Their Role in the Tumoral Microenvironment.Frontiers in cell and developmental biology · 2020Review
- Exploring the Origin and Antigenic Specificity of Maternal Regulatory T Cells in Pregnancy.Frontiers in immunology · 2020Review
- Midbrain microglia mediate a specific immunosuppressive response under inflammatory conditions.Journal of neuroinflammation · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several mechanisms of immune suppression have been attributed to Foxp3+ T regulatory cells (Treg) including modulation of target cells via inhibition of cell proliferation, alteration of cytokine secretion, and modification of cell phenotype, among others. Neuropilin-1 (Nrp1), a co-receptor protein highly expressed on Treg cells has been involved in tolerance-mediated responses, driving tumor growth and transplant acceptance. Here, we extend our previous findings showing that, despite expressing Foxp3,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.