Evidence map›Paper›PMID 31068905›Full record

ReviewFrontiers in endocrinology2019

Hypothyroidism as a Predictor of Surgical Outcomes in the Elderly.

Marco Vacante, Antonio Biondi, Francesco Basile, Roberto Ciuni, Salvatore Luca, Salomone Di Saverio, Carola Buscemi, Enzo Saretto Dante Vicari, Antonio Maria Borzì

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Hypothyroidism and Spine Surgery: a Review of Current Findings.Current reviews in musculoskeletal medicine · 2023
    Review
  5. Article
  6. Presence of preoperative Modic changes and severity of endplate damage score are independent risk factors for developing postoperative surgical site infection: a retrospective case-control study of 1124 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Article
  7. Review
  8. Nonthyroidal Illness Syndrome Across the Ages.Journal of the Endocrine Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Marco VacanteDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
Antonio BiondiDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
Francesco BasileDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
Roberto CiuniDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
Salvatore LucaDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
Salomone Di SaverioCambridge Colorectal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Carola BuscemiDepartment of Clinical and Experimental Medicine, Specialization School in Geriatrics, University of Catania, Catania, Italy.
Enzo Saretto Dante VicariDepartment of Clinical and Experimental Medicine, Specialization School in Geriatrics, University of Catania, Catania, Italy.
Antonio Maria BorzìDepartment of Clinical and Experimental Medicine, Specialization School in Geriatrics, University of Catania, Catania, Italy.
University of Catania · ITCambridge University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a high prevalence of hypothyroidism in the elderly population, mainly among women. The most important cause is autoimmune thyroiditis, but also iodine deficiency, radioiodine ablation, and surgery may be responsible for hypothyroidism in elderly hospitalized patients. Thyroid-related symptoms are sometimes comparable to physiological manifestations of the aging process, and hypothyroidism may be related with many symptoms which can be present in critical patients, such as cognitive impairment, cardiovascular, gastrointestinal, and hematological alterations, and eventually myxedema coma which is a severe and life-threatening condition in older adults. Adequate thyroid hormone levels are required to achieve optimal outcomes from any kind of surgical intervention. However, only few randomized clinical trials investigated the association between non-thyroidal illness (or low-T3 syndrome), and adverse surgical outcomes, so far. The goal of this review is to discuss the role of thyroid function as a predictor of surgical outcomes in the elderly.

Indexed as

elderlyhypothyroidismlow T3 syndromesurgerythyrotoxicosis

Identifiers

PMID31068905
PMCPMC6491643
OpenAlexW2941953203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.