Evidence map›Paper›PMID 31068789›Full record

ArticleFrontiers in molecular neuroscience2019

Oleoylethanolamide Modulates BDNF-ERK Signaling and Neurogenesis in the Hippocampi of Rats Exposed to Δ

Daniel Silva-Peña, Patricia Rivera, Francisco Alén, Antonio Vargas, Leticia Rubio, Nuria García-Marchena, Francisco Javier Pavón, Antonia Serrano, Fernando Rodríguez de Fonseca, Juan Suárez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  17. Iranian journal of basic medical sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Daniel Silva-PeñaInstituto de Investigación Biomédica de Málaga, U.G.C. de Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain.
Patricia RiveraDepartment of Endocrinology, Fundación Investigación Biomédica del Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Francisco AlénDepartamento de Psicobiología, Universidad Complutense Madrid, Pozuelo de Alarcón, Spain.
Antonio VargasInstituto de Investigación Biomédica de Málaga, U.G.C. de Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain.
Leticia RubioDepartamento de Anatomía y Medicina Legal, Universidad de Málaga, Málaga, Spain.
Nuria García-MarchenaInstituto de Investigación Biomédica de Málaga, U.G.C. de Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain.
Francisco Javier PavónInstituto de Investigación Biomédica de Málaga, U.G.C. de Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain.
Antonia SerranoInstituto de Investigación Biomédica de Málaga, U.G.C. de Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain.
Fernando Rodríguez de FonsecaInstituto de Investigación Biomédica de Málaga, U.G.C. de Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain.
Juan SuárezInstituto de Investigación Biomédica de Málaga, U.G.C. de Salud Mental, Hospital Regional Universitario de Málaga, Málaga, Spain.
Instituto de Investigación Biomédica de Málaga · ESHospital Regional Universitario de Málaga · ESHospital Infantil Universitario Niño Jesús · ESUniversidad Complutense de Madrid · ESUniversidad de Málaga · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oleoylethanolamide is an endogenous NAE that modulates ethanol-seeking behavior and ethanol-induced neuroinflammation. In the present study we further analyze the role of OEA in hippocampal neurogenesis, BDNF-ERK signaling, and spatial memory that are affected by alcohol. Additionally, we addressed the effects of OEA on the association of alcohol and cannabis, a frequent combination in human alcohol addicts, and whose long-term effects are far from being understood. To this end, OEA (10 mg/kg/day, i.p.) was pharmacologically administered for 5 days/week in a preclinical model of adolescent rats with binge-like consumption (1 day/week) of ethanol (3 g/kg, i.g.) combined or not with acute administrations of Δ

Indexed as

alcoholbrain-derived neurotrophic factorERKhippocampusmemoryoleoylethanolamide

Identifiers

PMID31068789
PMCPMC6491684
OpenAlexW2942271704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.