ArticleFrontiers in neuroscience2019
Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 29 citations in OpenAlex.
- Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits.Molecular autism · 2024Article
- The Neurotransmission Basis of Post-Traumatic Stress Disorders by the Fear Conditioning Paradigm.International journal of molecular sciences · 2023Review
- Increased dietary 5-hydroxytryptophan reduces fearfulness in red junglefowl hens (Frontiers in physiology · 2023Article
- Neural serotonergic circuits for controlling long-term voluntary alcohol consumption in mice.Molecular psychiatry · 2022Article
- Pharmacological Implications of Adjusting Abnormal Fear Memory: Towards the Treatment of Post-Traumatic Stress Disorder.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Dopamine and serotonin interplay for valence-based spatial learning.Cell reports · 2022Article
- Article
- Diet Prevents Social Stress-Induced Maladaptive Neurobehavioural and Gut Microbiota Changes in a Histamine-Dependent Manner.International journal of molecular sciences · 2022Article
- ZFPM1 Necessary for Development of Serotonergic Projections Related to Anxiety and Contextual Fear Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- REVERSE phenotyping-Can the phenotype following constitutive Tph2 gene inactivation in mice be transferred to children and adolescents with and without adhd?Brain and behavior · 2021Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain serotonin (5-hydroxytryptamine, 5-HT) system dysfunction is implicated in exaggerated fear responses triggering various anxiety-, stress-, and trauma-related disorders. However, the underlying mechanisms are not well understood. Here, we investigated the impact of constitutively inactivated 5-HT synthesis on context-dependent fear learning and extinction using tryptophan hydroxylase 2 (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.