Evidence map›Paper›PMID 31068623›Full record

ArticleScientific reports2019

Circulating tumor cells undergoing EMT are poorly correlated with clinical stages or predictive of recurrence in hepatocellular carcinoma.

Yunyang Chen, Shaoming Li, Wei Li, Rongbing Yang, Xianguang Zhang, Yong Ye, Jiexiong Yu, Lin Ye, Wangrong Tang

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Utility of Liquid Biopsy Analysis in Detection of Hepatocellular Carcinoma, Determination of Prognosis, and Disease Monitoring: A Systematic Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunyang ChenDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Shaoming LiDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Wei LiDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Rongbing YangDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Xianguang ZhangDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Yong YeDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Jiexiong YuDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Lin YeDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China.
Wangrong TangDepartment of Hepatobiliary Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong, China. tomy_van@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental and clinical studies have highlighted that circulating tumor cell (CTC) with phenotypic hallmarks of epithelial-mesenchymal transition (EMT) plays a critical role in the metastatic and recurrence of solid malignancy. Here we retrospectively evaluated the presence of CTC and its EMT phenotypes in hepatocellular carcinoma (HCC) patients and investigated their clinical relevance. We optimized the Canpatrol

Indexed as

Neoplasm Recurrence, LocalNeoplastic Cells, CirculatingPhenotypeBiomarkers, TumorCarcinoma, HepatocellularCell CountEpithelial Cell Adhesion MoleculeEpithelial-Mesenchymal TransitionFemaleHumansLiver NeoplasmsMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesBiomarkers, TumorEpithelial Cell Adhesion Molecule

Identifiers

PMID31068623
PMCPMC6506548

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.