Evidence map›Paper›PMID 31068436›Full record

ArticlemSphere2019

An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus.

Arsa Thammahong, Sourabh Dhingra, Katherine M Bultman, Joshua D Kerkaert, Robert A Cramer

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The mRNA stability factor Khd4 defines a specific mRNA regulon for membrane trafficking in the pathogenProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Chitin Biosynthesis inJournal of fungi (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Post-transcriptional control of fungal cell wall synthesis.Cell surface (Amsterdam, Netherlands) · 2022
    Article
  8. Genome Analyses of Two Blueberry Pathogens:Journal of fungi (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
  11. TheMicrobiology spectrum · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Novel Antifungal Agents and Their Activity againstJournal of fungi (Basel, Switzerland) · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. The Inhibitory Effect of Validamycin A onInternational journal of microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Arsa ThammahongDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Sourabh DhingraDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Katherine M BultmanDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Joshua D KerkaertDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Robert A CramerDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA Robert.A.Cramer.Jr@dartmouth.edu.
Dartmouth College · US

Funding

TRANSLATIONAL RESEARCH COREP30GM106394 · NIGMS · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2013 to 2017
$6.1M
HOST-MICROBE INTERACTIONST32AI007519 · NIAID · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 1997 to 2026
$5.9M
Hypoxia Adaptation and Fungal Virulence of Aspergillus fumigatusR01AI081838 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI CRAMER, ROBERT ANDREW · 2009 to 2017
$2.9M
NIAID NIH HHS R01 AI081838NIAID NIH HHS T32 AI007519NIGMS NIH HHS P30 GM106394
6 · The paper itself

Abstract

Regulation of fungal cell wall biosynthesis is critical to maintain cell wall integrity in dynamic fungal infection microenvironments. Genes involved in this response that impact fungal fitness and host immune responses remain to be fully defined. In this study, we observed that a yeast

Indexed as

AnimalsAspergillus fumigatusCell WallChitinDisease Models, AnimalFemaleFungal ProteinsGene Expression Regulation, FungalHomeostasisHost Microbial InteractionsInvasive Pulmonary AspergillosisMiceMutationSpores, FungalTrehaloseVirulenceChitinFungal ProteinsTrehaloseAspergillus fumigatuscell wallchitinpathogenesistrehalosevirulence

Identifiers

PMID31068436
PMCPMC6506620
OpenAlexW2950517197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.