Evidence map›Paper›PMID 31068431›Full record

ArticlemSphere2019

Internalization of Erythrocyte Acylpeptide Hydrolase Is Required for Asexual Replication of Plasmodium falciparum.

Rubayet Elahi, Christie Dapper, Michael Klemba

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Prodrug activation in malaria parasites mediated by an imported erythrocyte esterase, acylpeptide hydrolase (APEH).Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Metabolism of host lysophosphatidylcholine inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rubayet ElahiDepartment of Biochemistry, Virginia Tech, Blacksburg, Virginia, USA.
Christie DapperDepartment of Biochemistry, Virginia Tech, Blacksburg, Virginia, USA.
Michael KlembaDepartment of Biochemistry, Virginia Tech, Blacksburg, Virginia, USA klemba@vt.edu.ORCID 0000-0001-8827-6877
Virginia Tech · US

Funding

Chemo-proteomic discovery of lipases in asexual and sexual erythrocytic stages of Plasmodium falciparumR21AI133136 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KLEMBA, MICHAEL · 2017 to 2018
$380k
NIAID NIH HHS R21 AI133136
6 · The paper itself

Abstract

The human malaria parasite

Indexed as

Host-Parasite InteractionsReproduction, AsexualCells, CulturedErythrocytesHumansMalaria, FalciparumPeptide HydrolasesPlasmodium falciparumProtozoan Proteinsacylaminoacyl-peptidasePeptide HydrolasesProtozoan Proteinsacylpeptide hydrolaseerythrocytemalariaPlasmodiumserine hydrolase

Identifiers

PMID31068431
PMCPMC6506615
OpenAlexW2952931425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.