Evidence map›Paper›PMID 31068311›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2019

[Effects of CYP2D6

Qian Zhu, Weihua Lai, Liwen Li, Hanping Li, Shilong Zhong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Qian ZhuSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Weihua LaiDepartment of Pharmacy, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Liwen LiDepartment of Cardiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Hanping LiGuangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Shilong ZhongSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
Guangdong Academy of Medical Sciences · CNGuangdong Provincial People's Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the effect of CYP2D6

methodsThe patients with coronary artery disease taking metoprolol tablets (

resultsIn patients taking metoprolol sustained-release tablets, the plasma trough concentration of α-hydroxy metoprolol was significantly associated with the systolic blood pressure (

conclusionsCYP2D6

Indexed as

Coronary Artery DiseaseAdrenergic beta-AntagonistsChromatography, LiquidCytochrome P-450 CYP2D6GenotypeHumansMetoprololTandem Mass SpectrometryAdrenergic beta-AntagonistsCytochrome P-450 CYP2D6Metoprololblood pressureCYP2D6*10heart ratemetoprololtrough concentration

Identifiers

PMID31068311
PMCPMC6765674
OpenAlexW2991107511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.