Evidence map›Paper›PMID 31068234›Full record

ArticleBJPsych open2019

Clinical features of paediatric acute-onset neuropsychiatric syndrome: findings from a case- control study.

Eva Hesselmark, Susanne Bejerot

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Children With PANS May Manifest POTS.Frontiers in neurology · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. The Cunningham Panel: concerns remain.Translational psychiatry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Eva HesselmarkPhD Student, Department of Clinical Neuroscience, Center for Psychiatry Research,Karolinska Institutet; andStockholm Health Care Services,Stockholm County Council,Sweden.ORCID https://orcid.org/0000-0002-2205-4179
Susanne BejerotProfessor,School of Medical Sciences, Örebro University; University Health Care Research Center,Faculty of Medicine and Health, Örebro University; and Department of Clinical Neuroscience,Center for Psychiatry Research, Karolinska Institutet,Sweden.ORCID https://orcid.org/0000-0002-3587-6075
Örebro University · SEStockholm County Council · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPaediatric acute-onset neuropsychiatric syndrome (PANS), an umbrella term that includes PANDAS (paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) is suggested to be a psychiatric disorder of autoimmune aetiology. PANS is characterised by an acute onset of obsessive-compulsive disorder or restricted eating with multiple comorbid symptoms. The specificity of the PANS criteria is not fully understood.AimsTo describe a cohort of patients with PANS and to determine if PANS features relating to symptoms, onset and course are more common in PANS than in other psychiatric conditions.

methodA case-control study comparing patients with interview-confirmed PANS with patients with suspected PANS and patients with a psychiatric condition but with no suspicion of PANS. Validated and non-validated measures of symptoms, onset and episodic course were used.

resultsIllness in patients with interview-confirmed PANS featured an episodic course and multiple symptoms present at onset compared with the psychiatric controls. However, individuals with interview-confirmed PANS did not present a specific symptom profile.

conclusionsPANS may be a distinct clinical entity featuring an acute onset, an episodic course and multiple symptoms at onset.Declaration of interestNone.

Indexed as

diagnostic criteriaobsessive-compulsive disorderPediatric acute-onset neuropsychiatric syndromepediatric autoimmune neuropsychiatric disorders associated with streptococcal infections

Identifiers

PMID31068234
PMCPMC6401534
OpenAlexW2920084328

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.