Evidence map›Paper›PMID 31068187›Full record

ArticleRadiation oncology (London, England)2019

A comparative study of identical VMAT about two adjacent targets with and without fixed-jaw technique.

Kai Xie, Hongfei Sun, Liugang Gao, Tao Lin, Jianfeng Sui, Xinye Ni

Open access · goldAbstract readComparative Study
In one paragraph

Article in Radiation oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kai XieRadiotherapy Department, Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, 213003, People's Republic of China.
Hongfei SunRadiotherapy Department, Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, 213003, People's Republic of China.
Liugang GaoRadiotherapy Department, Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, 213003, People's Republic of China.
Tao LinRadiotherapy Department, Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, 213003, People's Republic of China.
Jianfeng SuiRadiotherapy Department, Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, 213003, People's Republic of China.
Xinye NiRadiotherapy Department, Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, 213003, People's Republic of China. nxy@njmu.edu.cn.
Changzhou No.2 People's Hospital · CNNanjing Medical University · CN

Funding

High-Level Medical Talents Training Project of Changzhou 2016CZLJ004National Natural Science Foundation of China 81871756outh Project of Changzhou Municipal Commission of Health and Family Planning QN201718the Municipal Social Development Project of the Changzhou City, Jiangsu Province, China CJ20180073
6 · The paper itself

Abstract

backgroundThe radiation transmission through the multileaf collimators is undesired in modern techniques such as volumetric modulated arc therapy (VMAT). According to identical plans, in this study, we aim to investigate the dosimetric impact of jaw tracking on the VMAT plans on two adjacent targets.

methodsTwo treatment plans were designed for eight pelvic (cervical) patients with two targets using the same optimization parameters. The original plan (O-plan) used automatically selected jaw positions. In the new plan (F-plan), the jaws were fixed to block two targets in two beams. The dosimetric parameters of the two plans were compared to evaluate the improvement of dose sparing for the body volume between two targets (named interOAR) in F-VMAT.

resultsThe mean dose of interOAR reduced significantly from 654.96 ± 113.38 cGy for O-VMAT, to 490.84 ± 80.26 cGy for F-VMAT (p = 0.018). The monitor units (MUs) in the F-plans were 1.49-fold higher than that in the O-plan. The F and O-plan performed similarly in target dose homogeneity. The differences in Dmax of spinal cord, Dmax of spinal cord planning organ at risk volume, and V20, V30, and V40 of the intestine were insignificant.

conclusionsVMAT plans with the fixed-jaw method can reduce the volume between two targets effectively. However, despite the plan quality, the method can only be used when the regular methods cannot reach the clinical requirements for critical organs because of additional MUs.

Indexed as

AlgorithmsHumansJawJaw Relation RecordMiddle AgedOrgans at RiskPelvic NeoplasmsPrognosisRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedAdjacent targetsDosimetryFixed-jawMLC transmissionVMAT

Identifiers

PMID31068187
PMCPMC6505249
OpenAlexW2947401674

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.