SynthesisBMC public health2019
Burden of varicella in Latin America and the Caribbean: findings from a systematic literature review.
Synthesis in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Healthcare resource use and costs of varicella and its complications: A systematic literature review.Human vaccines & immunotherapeutics · 2023Pooled it
- Pooled it
- Varicella zoster virus infection.Nature reviews. Disease primers · 2026Review
- Seroprevalence of varicella zoster virus in Colombia: A community-based mixture models study.IJID regions · 2025Article
- Review
- Clinical and economic burden of varicella in pediatric patients hospitalized in four institutions in Guatemala.PLOS global public health · 2025Article
- Association Between Climatic Factors and Varicella Incidence in Wuxi, East China, 2010-2019: Surveillance Study.JMIR public health and surveillance · 2024Article
- Differential diagnosis of exanthematous viruses during the 2022 Mpox outbreak in Minas Gerais, Brazil.Journal of clinical microbiology · 2024Article
- Varicella Outbreak Among Recent Arrivals to New York City, 2022-2024.MMWR. Morbidity and mortality weekly report · 2024Article
- Varicella pneumonia in an immunocompetent adult patient: Case report and review of the literature.Respiratory medicine case reports · 2024Article
- Delineating the Seasonality of Varicella and Its Association With Climate in the Tropical Country of Colombia.The Journal of infectious diseases · 2023Article
- Clinical efficacy and effectiveness of alternative varicella vaccination strategies: An overview of reviews.Reviews in medical virology · 2023Review
- Global varicella vaccination programs.Clinical and experimental pediatrics · 2022Article
- Worldwide Evolution of Vaccinable and Nonvaccinable Viral Skin Infections: Google Trends Analysis.JMIR dermatology · 2022Article
- Article
- Article
- Economic evaluation of varicella vaccination strategies in Jiangsu province, China: a decision-tree Markov model.Human vaccines & immunotherapeutics · 2021Article
- The comparison of seroconversion rates among different varicella vaccines administered Turkish children; MAV/06 and vOka.Human vaccines & immunotherapeutics · 2021Article
- Acceptance of varicella vaccination.Human vaccines & immunotherapeutics · 2021Article
- Specific Varicella-Related Complications and Their Decrease in Hospitalized Children after the Introduction of General Varicella Vaccination: Results from a Multicenter Pediatric Hospital Surveillance Study in Bavaria (Germany).Infectious diseases and therapy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 5 countries.
Funding
Abstract
backgroundVaricella is typically mild and self-limiting, but can be associated with complications and even death. The limited data available on varicella in Latin America and the Caribbean (LAC) indicate substantial burden in countries where varicella vaccine is not part of publicly funded childhood national immunization programs.
methodsA systematic literature review of published studies was complemented by "gray" literature on varicella incidence, complications, mortality, and economic consequences, in the absence and presence of universal varicella vaccination (UVV) in LAC.
resultsSeroprevalence data indicate that varicella is usually a disease of childhood in LAC. Varicella incidence rates, while unreliable in the absence of mandatory reporting, show a trend to increased incidence due to greater urbanization and population density. The introduction of UVV in national immunization programs has led to significant reductions in varicella incidence in these areas.
conclusionsVaricella continues to pose a substantial healthcare burden in LAC. The future introduction of UVV in additional countries is predicted to provide substantial reductions in cases, with important economic benefits. For countries that have already implemented UVV, the challenge is to maintain high rates of coverage and, where relevant, consider inclusion of a second dose to reduce breakthrough cases. Given the significant proportion of the region now implementing UVV, a regional recommendation in order to prevent any potential for age-shifts in varicella infection might be considered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.