Evidence map›Paper›PMID 31068158›Full record

Trial reportBMC psychiatry2019

Effects of Attentional Bias Modification on residual symptoms in depression: a randomized controlled trial.

Rune Jonassen, Catherine J Harmer, Eva Hilland, Luigi A Maglanoc, Brage Kraft, Michael Browning, Tore C Stiles, Vegard Ø Haaland, Torkil Berge, Nils Inge Landrø

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02658682 nacompletednot on this map

Secondary Prevention of Depression Applying an Experimental Attentional Bias Modification Procedure

TypeinterventionalSponsorUniversity of OsloRan2015 to 2017Enrolled350ConditionsMajor DepressionArmsAttention Bias Modification, Sham Attention Bias Modification
NCT05415306 naunknown statusnot on this mapstarted 2022, after this paper: background citation

An Emoji-based Attention Bias Modification Intervention for Depressive Symptom Severity in Young Adults

TypeinterventionalSponsorUniversiti Tunku Abdul RahmanRan2022 to 2024Enrolled120ConditionsDepressive Symptoms, Mood DisordersArmsAttention Bias Modification, Deep-breathing training, Sham Training
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Rune JonassenClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway. rune.jonassen@psykologi.uio.no.
Catherine J HarmerClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.
Eva HillandDivision of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway.
Luigi A MaglanocClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.
Brage KraftClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.
Michael BrowningComputational Psychiatry Laboratory, Department of Psychiatry, University of Oxford, Oxford Health NHS Trust, Oxford, UK.
Tore C StilesClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.
Vegard Ø HaalandClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.
Torkil BergeDivision of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway.
Nils Inge LandrøClinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway. n.i.landro@psykologi.uio.no.
University of Oslo · NODiakonhjemmet Hospital · NOSørlandet Sykehus · NOUniversity of Oxford · GB

Funding

Medical Research Council MR/N008103/1MRF_ MR/N008103/3
6 · The paper itself

Abstract

backgroundFollowing treatment, many depressed patients have significant residual symptoms. However, large randomised controlled trials (RCT) in this population are lacking. When Attention bias modification training (ABM) leads to more positive emotional biases, associated changes in clinical symptoms have been reported. A broader and more transparent picture of the true advantage of ABM based on larger and more stringent clinical trials have been requested. The current study evaluates the early effect of two weeks ABM training on blinded clinician-rated and self-reported residual symptoms, and whether changes towards more positive attentional biases (AB) would be associated with symptom reduction.

methodA total of 321 patients with a history of depression were included in a preregistered randomized controlled double-blinded trial. Patients were randomised to an emotional ABM paradigm over fourteen days or a closely matched control condition. Symptoms based on the Hamilton Rating Scale for Depression (HRSD) and Beck Depression Inventory II (BDI-II) were obtained at baseline and after ABM training.

resultsABM training led to significantly greater decrease in clinician-rated symptoms of depression as compared to the control condition. No differences between ABM and placebo were found for self-reported symptoms. ABM induced a change of AB towards relatively more positive stimuli for participants that also showed greater symptom reduction.

conclusionThe current study demonstrates that ABM produces early changes in blinded clinician-rated depressive symptoms and that changes in AB is linked to changes in symptoms. ABM may have practical potential in the treatment of residual depression.

trial registrationClinicalTrials.gov ID: NCT02658682 (retrospectively registered in January 2016).

Indexed as

Attentional BiasAdultCognitive Behavioral TherapyDepressive DisorderDouble-Blind MethodFemaleHumansMaleRetrospective StudiesTreatment OutcomeAttentional bias modificationClinical trialDepression

Identifiers

PMID31068158
PMCPMC6505271
OpenAlexW2949100972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.