Evidence map›Paper›PMID 31068077›Full record

ReviewCell cycle (Georgetown, Tex.)2019

Regulation of TORC2 function and localization by Rab5 GTPases in

Melissa N Locke, Jeremy Thorner

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Substrates of the MAPK Slt2: Shaping Yeast Cell Integrity.Journal of fungi (Basel, Switzerland) · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Melissa N Lockea Division of Biochemistry, Biophysics & Structural Biology, and Division of Cell & Developmental Biology, Department of Molecular and Cell Biology , University of California at Berkeley , Berkeley , CA , USA.ORCID 0000-0001-8162-1471
Jeremy Thornera Division of Biochemistry, Biophysics & Structural Biology, and Division of Cell & Developmental Biology, Department of Molecular and Cell Biology , University of California at Berkeley , Berkeley , CA , USA.ORCID 0000-0002-2583-500X
University of California, Berkeley · US

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
Yeast Protein Kinase Signaling Networks: Specificity, Regulation and FunctionR01GM021841 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI THORNER, JEREMY W. · 1985 to 2019
$11.8M
NIGMS NIH HHS R01 GM021841NIGMS NIH HHS T32 GM007232
6 · The paper itself

Abstract

The evolutionarily conserved Target of Rapamycin (TOR) complex-2 (TORC2) is an essential regulator of plasma membrane homeostasis in budding yeast (

Indexed as

Glycogen Synthase Kinase 3Guanine Nucleotide Exchange FactorsHumansMechanistic Target of Rapamycin Complex 2Models, Molecularrab5 GTP-Binding ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionUp-RegulationGlycogen Synthase Kinase 3Guanine Nucleotide Exchange FactorsMCK1 protein, S cerevisiaeMechanistic Target of Rapamycin Complex 2Muk1 protein, S cerevisiaerab5 GTP-Binding ProteinsSaccharomyces cerevisiae ProteinsendocytosisGrowth controlguanine nucleotidemutantsphosphorylationplasma membraneprotein kinase

Identifiers

PMID31068077
PMCPMC6592226
OpenAlexW2944382555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.