Evidence map›Paper›PMID 31067450›Full record

ArticleCell metabolism2019

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.

Mikolaj Ogrodnik, Yi Zhu, Larissa G P Langhi, Tamar Tchkonia, Patrick Krüger, Edward Fielder, Stella Victorelli, Rifqha A Ruswhandi, Nino Giorgadze, Tamar Pirtskhalava and 14 more

Abstract readPublished Erratum
In one paragraph

Article in Cell metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Targeting cellular senescence in dystrophinPharmacological research · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Modulation of senescent LeprStem cell research & therapy · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. The impact of cellular senescence on aging skeletal muscle.Frontiers in cell and developmental biology · 2025
    Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Mikolaj Ogrodnik
Yi Zhu
Larissa G P Langhi
Tamar Tchkonia
Patrick Krüger
Edward Fielder
Stella Victorelli
Rifqha A Ruswhandi
Nino Giorgadze
Tamar Pirtskhalava
Oleg Podgorni
Grigori Enikolopov
Kurt O Johnson
Ming Xu
Christine Inman
Allyson K Palmer
Marissa Schafer
Moritz Weigl
Yuji Ikeno
Terry C Burns
João F Passos
Thomas von Zglinicki
James L Kirkland
Diana Jurk

Funding

Medical Scientist Traning Program at Mayo ClinicT32GM065841 · NIGMS · MAYO CLINIC ROCHESTER · PI KAUFMANN, SCOTT H, SCHIMMENTI, LISA A · 2003 to 2022
$5.8M
Biotechnology and Biological Sciences Research Council BB/H022384/1Biotechnology and Biological Sciences Research Council BB/I020748/1Biotechnology and Biological Sciences Research Council BB/S006710/1Cancer Research UK 24009NIGMS NIH HHS T32 GM065841
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID31067450
PMCPMC6509279

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.