Trial reportPLoS medicine2019
Individualized decision aid for diverse women with lupus nephritis (IDEA-WON): A randomized controlled trial.
Trial report in PLoS medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02319525 (Individualized Patient Decision Making for Treatment Choices Among Minorities With Lupus), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Individualized Patient Decision Making for Treatment Choices Among Minorities With Lupus
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effects of patient decision aids used pre-consult or in-consult on patient-clinician communication - secondary analysis of a systematic review with meta-analysis.BMC medical informatics and decision making · 2025Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- A Systematic Review and Meta-Analysis of Patient Decision Aids for Socially Disadvantaged Populations: Update from the International Patient Decision Aid Standards (IPDAS).Medical decision making : an international journal of the Society for Medical Decision Making · 2021Pooled it
- The "good cancer" paradox: Decisional conflict and unmet support needs in patients with thyroid cancer facing surgical decisions-A mixed-methods study.Asia-Pacific journal of oncology nursing · 2026Article
- A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development.Arthritis care & research · 2026Article
- Patient outcomes from implementing a shared decision-making aid for systemic lupus erythematosus: a prospective implementation study.The Lancet. Rheumatology · 2026Article
- The impact of shared decision-making on quality of life in systemic lupus erythematosus practice: findings from the TRUMPFrontiers in immunology · 2026Observational
- Where, How, and How Much? A Multicenter Cohort Study of the Relationship Across Lupus Decision-Aid Modality, Place of Administration, Interruption and Viewing Completeness, and Patient-Reported Outcomes.Arthritis care & research · 2025Observational
- Implementation outcomes of a patient decision-aid in a diverse population with systemic lupus erythematosus in 15 US rheumatology clinics.Rheumatology (Oxford, England) · 2025Article
- Barriers to and facilitators of sustaining a systemic lupus erythematosus (SLE) patient decision aid in regular rheumatology outpatient care in the USA.Rheumatology (Oxford, England) · 2025Observational
- Time required to implement a computerized patient decision aid for lupus in outpatient visits.Implementation science communications · 2025Article
- Medication decision making under uncertainty: Considering chronic disease and pregnancy potential.Seminars in perinatology · 2025Review
- Can health information and decision aids decrease inequity in health care? A systematic review.BMJ public health · 2025Article
- E-Health Interventions to Improve Health Outcomes in Patients with Systemic Lupus Erythematosus: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Clarifying misbeliefs about hydroxychloroquine (HCQ): developing the HCQ benefits versus harm decision aid (HCQ-SAFE) per low health literacy standards.Lupus science & medicine · 2023Article
- Patient-centred clinical trial design.Nature reviews. Nephrology · 2022Review
- Information preferences about treatment options in diffuse cutaneous systemic sclerosis: A Delphi consensus study.Journal of scleroderma and related disorders · 2022Article
- A Focus Group Study of Self-Management in Patients With Glomerular Disease.Kidney international reports · 2022Article
- Implementing the DEcision-Aid for Lupus (IDEAL): study protocol of a multi-site implementation trial with observational, case study design : Implementing the DEcision-Aid for Lupus.Implementation science communications · 2021Article
- Impact of Limited Health Literacy on Patient-Reported Outcomes in Systemic Lupus Erythematosus.Arthritis care & research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Funding
Abstract
backgroundTreatment decision-making regarding immunosuppressive therapy is challenging for individuals with lupus. We assessed the effectiveness of a decision aid for immunosuppressive therapy in lupus nephritis. METHODS AND
findingsIn a United States multicenter, open-label, randomized controlled trial (RCT), adult women with lupus nephritis, mostly from racial/ethnic minority backgrounds with low socioeconomic status (SES), seen in in- or outpatient settings, were randomized to an individualized, culturally tailored, computerized decision aid versus American College of Rheumatology (ACR) lupus pamphlet (1:1 ratio), using computer-generated randomization. We hypothesized that the co-primary outcomes of decisional conflict and informed choice regarding immunosuppressive medications would improve more in the decision aid group. Of 301 randomized women, 298 were analyzed; 47% were African-American, 26% Hispanic, and 15% white. Mean age (standard deviation [SD]) was 37 (12) years, 57% had annual income of <$40,000, and 36% had a high school education or less. Compared with the provision of the ACR lupus pamphlet (n = 147), participants randomized to the decision aid (n = 151) had (1) a clinically meaningful and statistically significant reduction in decisional conflict, 21.8 (standard error [SE], 2.5) versus 12.7 (SE, 2.0; p = 0.005) and (2) no difference in informed choice in the main analysis, 41% versus 31% (p = 0.08), but clinically meaningful and statistically significant difference in sensitivity analysis (net values for immunosuppressives positive [in favor] versus negative [against]), 50% versus 35% (p = 0.006). Unresolved decisional conflict was lower in the decision aid versus pamphlet groups, 22% versus 44% (p < 0.001). Significantly more patients in the decision aid versus pamphlet group rated information to be excellent for understanding lupus nephritis (49% versus 33%), risk factors (43% versus 27%), medication options (50% versus 33%; p ≤ 0.003 for all); and the ease of use of materials was higher in the decision aid versus pamphlet groups (51% versus 38%; p = 0.006). Key study limitations were the exclusion of men, short follow-up, and the lack of clinical outcomes, including medication adherence.
conclusionsAn individualized decision aid was more effective than usual care in reducing decisional conflict for choice of immunosuppressive medications in women with lupus nephritis.
trial registrationClinicaltrials.gov, NCT02319525.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.