Trial reportAIDS patient care and STDs2019
CHAMP+ Thailand: Pilot Randomized Control Trial of a Family-Based Psychosocial Intervention for Perinatally HIV-Infected Early Adolescents.
Trial report in AIDS patient care and STDs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Primary-level and community worker interventions for the prevention of mental disorders and the promotion of well-being in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Effect of Social Support Interventions on Adherence to Antiretroviral Therapy Among People Living with HIV: A Systematic Review and Meta-Analysis.AIDS and behavior · 2023Pooled it
- Psychosocial interventions for improving engagement in care and health and behavioural outcomes for adolescents and young people living with HIV: a systematic review and meta-analysis.Journal of the International AIDS Society · 2021Pooled it
- Peer-led counselling with problem discussion therapy for adolescents living with HIV in Zimbabwe: A cluster-randomised trial.PLoS medicine · 2022Trial
- Relationship Between Mental Health and HIV Transmission Knowledge and Prevention Attitudes Among Adolescents Living with HIV: Lessons from Suubi + Adherence Cluster Randomized Study in Southern Uganda.AIDS and behavior · 2021Trial
- A group-based mental health intervention for young people living with HIV in Tanzania: results of a pilot individually randomized group treatment trial.BMC public health · 2020Trial
- Interventions Supporting Disclosure Among Children and Adolescents Living with HIV: A Scoping Review and Realist Synthesis.AIDS and behavior · 2026Article
- Health educational interventions for adolescents living with HIV: A scoping review.International journal of nursing studies advances · 2025Review
- Digital Motion Graphics and Animated Media in Health Communication: A Systematic Review of Strategies for Sexual Health Messaging.Healthcare (Basel, Switzerland) · 2025Review
- A Scoping Review of Graphic Medicine Interventions to Promote Changes in Health Behavior, Health Service Engagement, and Health Outcomes.International journal of environmental research and public health · 2025Article
- Enhancing HIV Cognitive Abilities and Self-Management Through Information Technology-Assisted Interventions: Scoping Review.Journal of medical Internet research · 2025Article
- Violence as an obstacle to HIV medication adherence and viral suppression: A daily diary investigation among adolescent boys.Social science & medicine (1982) · 2025Article
- Intervention measures for stigma in HIV patients: a scoping review of randomized controlled trials.Frontiers in public health · 2025Article
- HIV-related stressors and psychological functioning among adolescents living with perinatal HIV in KwaZulu-Natal, South Africa.Frontiers in public health · 2025Article
- "We did more than survive": lessons learned from studies of risk and resilience of young people growing up with HIV and mental health needs.AIDS care · 2024Article
- Advancing Adolescent and Young Adult HIV Prevention and Care and Treatment Through Use of Multi-level Theories and Frameworks: A Scoping Review and Adapted HIV Ecological Framework.AIDS and behavior · 2024Article
- The effect of group support psychotherapy on adherence to anti-retroviral therapy and viral suppression among HIV positive young people: Study protocol for a pilot randomized controlled trial.Frontiers in health services · 2023Article
- Central Nervous System Impact of Perinatally Acquired HIV in Adolescents and Adults: an Update.Current HIV/AIDS reports · 2022Review
- Interventions to address the mental health of adolescents and young adults living with or affected by HIV: state of the evidence.Journal of the International AIDS Society · 2021Review
- Mental health interventions for adolescents living with HIV or affected by HIV in low- and middle-income countries: systematic review.BJPsych open · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Within Asia, HIV prevalence is highest in Thailand, including thousands of children and adolescents. Care for children born with HIV [perinatal transmission of HIV (PHIV)] will need to focus on adolescents for the foreseeable future. Thai PHIV adolescents experience significant mental health and psychosocial challenges, including treatment adherence. Yet, few, if any, comprehensive interventions for them exist. CHAMP+, an evidence-based intervention adapted for Thailand, was evaluated with a pilot randomized control trial at four HIV clinics. Eighty-eight dyads of 9- to 14-year-old PHIV young adolescents/caregivers were randomized to CHAMP+ or standard of care (SOC). Eleven cartoon-based sessions were delivered over 6 months. Participants completed baseline, 6-month (postintervention), and 9-month surveys, measuring youth outcomes (e.g., mental health and adherence), contextual factors (e.g., demographics and caregiver factors), and self- and social-regulation factors (e.g., HIV knowledge and youth-caregiver communication). Multi-level modeling to account for clustering within individuals was used to assess longitudinal changes within and between groups. All families randomized to CHAMP+ completed the intervention. Although the study was not statistically powered to detect differences in treatment effects, the CHAMP+ group significantly improved at 6 months in youth mental health and adherence, HIV knowledge, youth-caregiver communication, internalized stigma, and HIV-related social support, with most improvements sustained at 9 months and significantly better improvements than the SOC group on a number of outcomes. High levels of baseline viral suppression highlight the importance of reaching these young PHIV adolescents at a period of lower risk before adherence and other challenges emerge. Designed to be delivered with limited cost/resources, CHAMP+ Thailand holds scale-up potential.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.