ReviewThe British journal of radiology2019
Nigrosome 1 imaging: technical considerations and clinical applications.
Review in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is the Swallow Tail Sign a Useful Imaging Biomarker in Clinical Neurology? A Systematic Review.Movement disorders clinical practice · 2025Pooled it
- The swallow tail sign: mechanisms, neuroimaging advances and future perspectives.Insights into imaging · 2026Article
- Editorial for "Comparison of Diagnostic Performance Between Standard Susceptibility Map-Weighted Imaging and Susceptibility Map-Weighted Imaging Reconstructed From Clinical SWI and Neuromelanin MRI in Early Parkinson's Disease".Journal of magnetic resonance imaging : JMRI · 2026Article
- Comparison of Diagnostic Performance Between Standard Susceptibility Map-Weighted Imaging and Susceptibility Map-Weighted Imaging Reconstructed From Clinical SWI and Neuromelanin MRI in Early Parkinson's Disease.Journal of magnetic resonance imaging : JMRI · 2026Article
- Neuroimaging of the monoaminergic system in Parkinson's disease: A narrative review.Neuroimage. Reports · 2026Review
- [MRI in neurodegenerative Parkinsonian syndromes].Radiologie (Heidelberg, Germany) · 2026Review
- Effect of Deep Learning-Based Artificial Intelligence on Radiologists' Performance in Identifying Nigrosome 1 Abnormalities on Susceptibility Map-Weighted Imaging.Korean journal of radiology · 2025Article
- High-resolution mapping of substantia nigra in Parkinson's disease using 7 tesla magnetic resonance imaging.NPJ Parkinson's disease · 2025Article
- Susceptibility map-weighted MRI can distinguish tremor-dominant Parkinson's disease from essential tremor.Scientific reports · 2025Article
- Increased mean diffusivity of the caudal motor SNc identifies patients with REM sleep behaviour disorder and Parkinson's disease.NPJ Parkinson's disease · 2024Article
- Comparative Performance of Susceptibility Map-Weighted MRI According to the Acquisition Planes in the Diagnosis of Neurodegenerative Parkinsonism.Korean journal of radiology · 2024Observational
- Increased iron in the substantia nigra pars compacta identifies patients with early Parkinson'sdisease: A 3T and 7T MRI study.NeuroImage. Clinical · 2024Article
- [Brain MRI-Based Artificial Intelligence Software in Patients with Neurodegenerative Diseases: Current Status].Taehan Yongsang Uihakhoe chi · 2022Review
- Asymmetric Parkinsonism With Progressive Nigrosomal Change Secondary to Kernohan's Notch Phenomenon.Journal of movement disorders · 2022Article
- Modified Iron Deposition in Nigrosomes by Pharmacotherapy for the Management of Parkinson's Disease.Frontiers in molecular biosciences · 2022Article
- Pragmatic Approach on Neuroimaging Techniques for the Differential Diagnosis of Parkinsonisms.Movement disorders clinical practice · 2022Review
- Measuring the iron content of dopaminergic neurons in substantia nigra with MRI relaxometry.NeuroImage · 2021Article
- Fast 3 T nigral hyperintensity magnetic resonance imaging in Parkinson's disease.Scientific reports · 2021Article
- Substantia Nigra Radiomics Feature Extraction of Parkinson's Disease Based on Magnitude Images of Susceptibility-Weighted Imaging.Frontiers in neuroscience · 2021Article
- Do the Magic Angle Effects or Susceptibility Effects Affect the Visualization of Nigrosome 1?AJNR. American journal of neuroradiology · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A pathological study by Damier et al demonstrated that nigrosome 1, a dopaminergic neuron-rich region in the substantial nigra, is the most severely affected region in idiopathic Parkinson's disease. Since then, researchers have identified the location of nigrosome 1 in the dorsal aspect of the substantia nigra using susceptibility-weighted imaging in MRI. Although this observation was reconfirmed by various imaging techniques and imaging planes, non-standardized imaging methods may rather limit the generalized use of this imaging finding. The aim of this review is to revisit the anatomical definition of the nigrosome 1 region using high-spatial-resolution susceptibility map-weighted MRI in order to help the readers to determine the presence or absence of an abnormality in the nigrosome 1 region. Thereafter, we discuss the current status of nigrosome 1 imaging at 3 T and show how to improve the imaging quality for better assessment of nigrosome 1. We also illustrate the imaging findings of various patients who presented with parkinsonism, which can help the readers to learn how to use these images in practice. Lastly, we discuss potential future works with nigrosome 1 susceptibility map-weighted MRI.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.