ArticleHuman brain mapping2019
Intensity-related distribution of sweet and bitter taste fMRI responses in the insular cortex.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Engaging visual media shifts taste-related neural processing: An fMRI study on distracted eating.Neuroimage. Reports · 2026Article
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- Central Regulation of Eating Behaviors in Humans: Evidence from Functional Neuroimaging Studies.Nutrients · 2023Review
- Functional MRI activation of the nucleus tractus solitarius after taste stimuli at ultra-high field: a proof-of-concept single-subject study.Frontiers in nutrition · 2023Article
- Encoding Taste: From Receptors to Perception.Handbook of experimental pharmacology · 2022Article
- Neurosensory development of the four brainstem-projecting sensory systems and their integration in the telencephalon.Frontiers in neural circuits · 2022Article
- Cellular activity in insular cortex across seconds to hours: Sensations and predictions of bodily states.Neuron · 2021Review
- Quantitatively Recognizing Stimuli Intensity of Primary Taste Based on Surface Electromyography.Sensors (Basel, Switzerland) · 2021Article
- Qualitative Recognition of Primary Taste Sensation Based on Surface Electromyography.Sensors (Basel, Switzerland) · 2021Article
- Against gustotopic representation in the human brain: There is no Cartesian Restaurant.Current opinion in physiology · 2021Article
- Sweet Taste Is Complex: Signaling Cascades and Circuits Involved in Sweet Sensation.Frontiers in human neuroscience · 2021Review
- The neuroscience of sugars in taste, gut-reward, feeding circuits, and obesity.Cellular and molecular life sciences : CMLS · 2020Review
- Macroscopic information-based taste representations in insular cortex are shaped by stimulus concentration.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Intensity-related distribution of sweet and bitter taste fMRI responses in the insular cortex.Human brain mapping · 2019Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human gustatory cortex analyzes the chemosensory properties of tastants, particularly the quality, intensity, and affective valence, to determine whether a perceived substance should be ingested or rejected. Among previous studies, the spatial distribution of taste intensity-related activations within the human insula has been scarcely addressed. To spatially characterize a specialized or distributed nature of the cortical responses to taste intensities, a functional magnetic resonance imaging study was performed at 3 T in 44 healthy subjects where sweet and bitter tastants were administered at five increasing concentrations and cortex-based factorial and parametric analyses were performed. Two clusters in the right middle-posterior and left middle insula were found specialized for taste intensity processing, exhibiting a highly nonlinear profile across concentrations. Multiple clusters were found activated by sweet and bitter taste stimuli at most concentrations, in the anterior, middle-posterior, and inferior portion of the bilateral insula. Across these clusters, respectively, for the right and left insula, a superior-to-inferior and an anterior-to-posterior spatial gradient for high-to-low concentrations were observed for the most responsive intensity of both tastes. These findings may gather new insights regarding how the gustatory cortex is spatially organized during the perceptual processing of taste intensity for two basic tastants.
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