ArticleArchives of endocrinology and metabolism
Arterial stiffness in hyperthyroid patients is deteriorated due to thyroid hormones.
Article in Archives of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- The Differential Effects of Propylthiouracil and Methimazole as Graves' Disease Treatment on Vascular Atherosclerosis Markers: A Randomized Clinical Trial.Frontiers in endocrinology · 2021Trial
- The association between T4 and TSH with lipid profile is attenuated in patients with established dyslipidemia.BMC endocrine disorders · 2026Article
- Thyroid storm-induced cardiovascular complications and modalities of therapy: Up-to-date review.World journal of critical care medicine · 2025Review
- Longitudinal Bone Density During TSH Suppression in Differentiated Thyroid Cancer: A Paired PET/CT Analysis.Cancers · 2025Article
- Evaluating the association between pulse wave velocity, augmentation index, serum TSH levels, and the prevalence of thyroid nodules in a Persian adult cohort: a cross-sectional study.Journal of diabetes and metabolic disorders · 2025Article
- Associations of Thyroid and Parathyroid Hormones with Arterial Stiffness in Emergency Department Patients: A Prospective Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- Haemodynamics of hyperthyroidism: increased cardiac work and findings related to vasodilatation.European thyroid journal · 2024Article
- Arterial Stiffness in Thyroid and Parathyroid Disease: A Review of Clinical Studies.Journal of clinical medicine · 2022Review
- Cardiac manifestations in hyperthyroidism.Reviews in cardiovascular medicine · 2022Review
- Meta-analysis on the Association Between Thyroid Hormone Disorders and Arterial Stiffness.Journal of the Endocrine Society · 2022Review
- Yearly Incidence of Stroke and Bleeding in Atrial Fibrillation with Concomitant Hyperthyroidism: A National Discharge Database Study.Journal of clinical medicine · 2022Article
- Elevated pulse pressure correlated with reduced retinal peripapillary capillary in thyroid-associated ophthalmology with visual field defect.Frontiers in endocrinology · 2022Article
- Association of thyroid hormones with blood pressure and arterial stiffness in the general population: The Dali study.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Central and peripheral blood pressures and arterial stiffness increase in hypoparathyroidism.Archives of endocrinology and metabolism · 2020Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study is to evaluate and compare arterial stiffness, which is an independent risk indicator for cardiovascular diseases (CVDs), between patients with overt hyperthyroidism, subclinical hyperthyroidism, euthyroidism by antithyroid therapy and healthy volunteers with pulse wave analysis (PWA). SUBJECTS AND
methodsA total of 102 volunteers were included in the study (30 in the overt hyperthyroid group, 28 in the subclinical hyperthyroid group and 14 with euthyroidism by antithyroid therapy and 30 healthy). The arterial stiffness measurements of the participants in the study were performed with the Mobil-O-Graph PWA device (I.E.M. GmBH, Stolberg, Germany), which makes cuff based oscillometric measurement from the brachial artery.
resultsSystolic blood pressure, pulse rate, central systolic blood pressure, cardiac output, heart rate-corrected augmentation index (Aix@75) and pulse wave velocity (PWV) measurements were significantly higher in the hyperthyroid group than in the control group. The heart rate and PWV in the subclinical hyperthyroid group were significantly higher than the control group. In the euthyroid group, systolic blood pressure, central systolic blood pressure, cardiac output, cardiac index and PWV were found significantly higher than the control group. There was also a negative correlation between Aix@75 and thyroid-stimulating hormone (TSH), and a positive correlation between Aix@75 and free thyroid hormones.
conclusionIn our study, we observed that the arterial stiffness was adversely affected by an overt or subclinical increase in thyroid hormones and this correlated with thyroid hormone levels. We recommend that PWV measurement, which is a simple method for detecting CVD risk, can be used in these patients.
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