ArticleJournal of neurophysiology2019
Motor module generalization across balance and walking is impaired after stroke.
Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 62 citations in OpenAlex.
- Beyond Pain Intensity: A Patient-Informed Framework for Documenting Burden in Small Fiber Neuropathy.Neurology and therapy · 2026Review
- Analysis of the correlation between lower limb muscle synergy characteristics and landing load during single-leg landing in humans.Scientific reports · 2026Article
- Effects of different post-activation potentiation strategies on forehand stroke performance in elite squash players: a muscle synergy and time-frequency coherence analysis.BMC sports science, medicine & rehabilitation · 2026Article
- Generalizability of neuromuscular coordination in the human upper extremity after stroke and its implications in neurorehabilitation.Journal of neuroengineering and rehabilitation · 2025Article
- Article
- Generalizability of motor modules across walking-based and in-place tasks - a distribution-based analysis on total knee replacement patients.Frontiers in bioengineering and biotechnology · 2025Article
- Delayed Cortical Responses During Reactive Balance After Stroke Associated With Slower Kinetics and Clinical Balance Dysfunction.Neurorehabilitation and neural repair · 2025Article
- Analysis of muscle synergy in the lower extremities and associated adaptive strategies during single-leg landing.Frontiers in physiology · 2025Article
- Application of Muscle Synergies for Gait Rehabilitation After Stroke: Implications for Future Research.Neurology international · 2024Review
- The cognitive neuroscience and neurocognitive rehabilitation of dance.BMC neuroscience · 2024Review
- Ethnokinesiology: towards a neuromechanical understanding of cultural differences in movement.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Increased trial-to-trial similarity and reduced temporal overlap of muscle synergy activation coefficients manifest during learning and with increasing movement proficiency.Scientific reports · 2024Article
- Muscle synergies are shared across fundamental subtasks in complex movements of skateboarding.Scientific reports · 2024Article
- NSF DARE-Transforming modeling in neurorehabilitation: Four threads for catalyzing progress.Journal of neuroengineering and rehabilitation · 2024Review
- Compensatory increase in ipsilesional supplementary motor area and premotor connectivity is associated with greater gait impairments: a personalized fMRI analysis in chronic stroke.Frontiers in human neuroscience · 2024Article
- Delayed cortical engagement associated with balance dysfunction after stroke.medRxiv : the preprint server for health sciences · 2023Article
- Discovering individual-specific gait signatures from data-driven models of neuromechanical dynamics.PLoS computational biology · 2023Article
- Muscle synergies for evaluating upper limb in clinical applications: A systematic review.Heliyon · 2023Review
- Nonlinear functional muscle network based on information theory tracks sensorimotor integration post stroke.Scientific reports · 2022Article
- Proprioceptive Neuromuscular Facilitation-Based Physical Therapy on the Improvement of Balance and Gait in Patients with Chronic Stroke: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Muscle coordination is often impaired after stroke, leading to deficits in the control of walking and balance. In this study, we examined features of muscle coordination associated with reduced walking performance in chronic stroke survivors using motor module (a.k.a. muscle synergy) analysis. We identified differences between stroke survivors and age-similar neurotypical controls in the modular control of both overground walking and standing reactive balance. In contrast to previous studies that demonstrated reduced motor module number poststroke, our cohort of stroke survivors did not exhibit a reduction in motor module number compared with controls during either walking or reactive balance. Instead, the pool of motor modules common to walking and reactive balance was smaller, suggesting reduced generalizability of motor module function across behaviors. The motor modules common to walking and reactive balance tended to be less variable and more distinct, suggesting more reliable output compared with motor modules specific to either behavior. Greater motor module generalization in stroke survivors was associated with faster walking speed, more normal step length asymmetry, and narrower step widths. Our work is the first to show that motor module generalization across walking and balance may help to distinguish important and clinically relevant differences in walking performance across stroke survivors that would have been overlooked by examining only a single behavior. Finally, because similar relationships between motor module generalization and walking performance have been demonstrated in healthy young adults and individuals with Parkinson's disease, this suggests that motor module generalization across walking and balance may be important for well-coordinated walking.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.