ArticleJournal of tissue engineering and regenerative medicine2019
Optimization of photocrosslinked gelatin/hyaluronic acid hybrid scaffold for the repair of cartilage defect.
Article in Journal of tissue engineering and regenerative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Pooled it
- Autologous Chondrocyte Implantation on Polyethersulfone Scaffolds in a Rabbit Model of Grade III Lesions.Molecules (Basel, Switzerland) · 2026Article
- GelMA Hydrogel/Alginate-Based Scaffolds: 3D Bioprinting for Cartilage Tissue Engineering.Tissue engineering and regenerative medicine · 2026Article
- VEGF-neutralized platelet-rich plasma with adipose-derived stromal vascular fraction enhanced osteochondral repair in a point-of-care goat model.Journal of orthopaedic translation · 2026Article
- Viscoelasticity Can Be Tuned Through Covalent Incorporation of Chondroitin Sulphate in Allylated Gelatin Hydrogels.Macromolecular bioscience · 2025Article
- An ideal biomaterial: Ti-based bone repair material with dual-response antibacterial system and sustained drug release.Frontiers in bioengineering and biotechnology · 2025Article
- Harnessing the potential of hyaluronic acid methacrylate (HAMA) hydrogel for clinical applications in orthopaedic diseases.Journal of orthopaedic translation · 2025Review
- Gelatin-Based Polymers Can Be Processed to Highly Resilient Biocompatible Porous Hydrogel Scaffolds for Soft Tissue Regeneration Applications.Gels (Basel, Switzerland) · 2024Article
- Tissue engineering strategies hold promise for the repair of articular cartilage injury.Biomedical engineering online · 2024Review
- Research progress of gene therapy combined with tissue engineering to promote bone regeneration.APL bioengineering · 2024Review
- Hydrogel-Based 3D Bioprinting Technology for Articular Cartilage Regenerative Engineering.Gels (Basel, Switzerland) · 2024Review
- Tissue engineering and future directions in regenerative medicine for knee cartilage repair: a comprehensive review.Croatian medical journal · 2024Review
- Osteochondral tissue engineering in translational practice: histological assessments and scoring systems.Frontiers in bioengineering and biotechnology · 2024Review
- A Photopolymerizable Biocompatible Hyaluronic Acid Hydrogel Promotes Early Articular Cartilage Repair in a Minipig Model In Vivo.Advanced healthcare materials · 2023Article
- In Vitro Analysis of Human Cartilage Infiltrated by Hydrogels and Hydrogel-Encapsulated Chondrocytes.Bioengineering (Basel, Switzerland) · 2023Article
- Article
- Scaffolds for Cartilage Tissue Engineering from a Blend of Polyethersulfone and Polyurethane Polymers.Molecules (Basel, Switzerland) · 2023Article
- Strategy insight: Mechanical properties of biomaterials' influence on hydrogel-mesenchymal stromal cell combination for osteoarthritis therapy.Frontiers in pharmacology · 2023Review
- Designing functional hyaluronic acid-based hydrogels for cartilage tissue engineering.Materials today. Bio · 2022Review
- PEG Reinforced Scaffold Promotes Uniform Distribution of Human MSC-Created Cartilage Matrix.Gels (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
There is no therapy currently available for fully repairing articular cartilage lesions. Our laboratory has recently developed a visible light-activatable methacrylated gelatin (mGL) hydrogel, with the potential for cartilage regeneration. In this study, we further optimized mGL scaffolds by supplementing methacrylated hyaluronic acid (mHA), which has been shown to stimulate chondrogenesis via activation of critical cellular signalling pathways. We hypothesized that the introduction of an optimal ratio of mHA would enhance the biological properties of mGL scaffolds and augment chondrogenesis of human bone marrow-derived mesenchymal stem cells (hBMSCs). To test this hypothesis, hybrid scaffolds consisting of mGL and mHA at different weight ratios were fabricated with hBMSCs encapsulated at 20 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.