Evidence map›Paper›PMID 31066453›Full record

ArticleNucleic acids research2019

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update).

Uku Raudvere, Liis Kolberg, Ivan Kuzmin, Tambet Arak, Priit Adler, Hedi Peterson, Jaak Vilo

Abstract read
In one paragraph

Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3,296 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3,296citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3,296 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Allele-specific expression in the brain links genetic risk and cortical thinning in psychiatric disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  14. BeWo-Derived Extracellular Vesicles Downregulate IL-6Rα Expression via miRNAs on CD4+ T Lymphocytes.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
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3,236 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Uku RaudvereInstitute of Computer Science, University of Tartu, J. Liivi 2, 50409 Tartu, Estonia.
Liis KolbergInstitute of Computer Science, University of Tartu, J. Liivi 2, 50409 Tartu, Estonia.
Ivan KuzminInstitute of Computer Science, University of Tartu, J. Liivi 2, 50409 Tartu, Estonia.
Tambet ArakInstitute of Computer Science, University of Tartu, J. Liivi 2, 50409 Tartu, Estonia.
Priit AdlerInstitute of Computer Science, University of Tartu, J. Liivi 2, 50409 Tartu, Estonia.
Hedi PetersonInstitute of Computer Science, University of Tartu, J. Liivi 2, 50409 Tartu, Estonia.
Jaak ViloInstitute of Computer Science, University of Tartu, J. Liivi 2, 50409 Tartu, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological data analysis often deals with lists of genes arising from various studies. The g:Profiler toolset is widely used for finding biological categories enriched in gene lists, conversions between gene identifiers and mappings to their orthologs. The mission of g:Profiler is to provide a reliable service based on up-to-date high quality data in a convenient manner across many evidence types, identifier spaces and organisms. g:Profiler relies on Ensembl as a primary data source and follows their quarterly release cycle while updating the other data sources simultaneously. The current update provides a better user experience due to a modern responsive web interface, standardised API and libraries. The results are delivered through an interactive and configurable web design. Results can be downloaded as publication ready visualisations or delimited text files. In the current update we have extended the support to 467 species and strains, including vertebrates, plants, fungi, insects and parasites. By supporting user uploaded custom GMT files, g:Profiler is now capable of analysing data from any organism. All past releases are maintained for reproducibility and transparency. The 2019 update introduces an extensive technical rewrite making the services faster and more flexible. g:Profiler is freely available at https://biit.cs.ut.ee/gprofiler.

Indexed as

Databases, GeneticGenomeInformation Storage and RetrievalSoftwareAnimalsFungiHumansParasitesPlants

Identifiers

PMID31066453
PMCPMC6602461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.