Evidence map›Paper›PMID 31066165›Full record

ArticleJournal of cellular and molecular medicine2019

MiR-21 is up-regulated in urinary exosomes of chronic kidney disease patients and after glomerular injury.

Tim Lange, Nadine Artelt, Frances Kindt, Sylvia Stracke, Rainer Rettig, Uwe Lendeckel, Christos E Chadjichristos, Panagiotis Kavvadas, Christos Chatziantoniou, Karlhans Endlich and 1 more

Abstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Article
  7. The role of extracellular vesicles in kidney disease progression.Kidney research and clinical practice · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Type I IFN in Glomerular Disease: Scarring beyond the STING.International journal of molecular sciences · 2024
    Review
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  14. Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tim LangeDepartment of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.ORCID 0000-0002-0716-7845
Nadine ArteltDepartment of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Frances KindtDepartment of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Sylvia StrackeDepartment of Internal Medicine A, University Medicine Greifswald, Greifswald, Germany.
Rainer RettigInstitute of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Uwe LendeckelDepartment of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Greifswald, Germany.
Christos E ChadjichristosUnité Mixte de Recherche (UMR)-S1155, Tenon Hospital, National Institute for Health and Medical Research (INSERM), Sorbonne Universités, Paris, France.
Panagiotis KavvadasUnité Mixte de Recherche (UMR)-S1155, Tenon Hospital, National Institute for Health and Medical Research (INSERM), Sorbonne Universités, Paris, France.
Christos ChatziantoniouUnité Mixte de Recherche (UMR)-S1155, Tenon Hospital, National Institute for Health and Medical Research (INSERM), Sorbonne Universités, Paris, France.
Karlhans EndlichDepartment of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Nicole EndlichDepartment of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultCell DedifferentiationExosomesFemaleGlomerular Filtration RateHumansKidney GlomerulusMaleMicroRNAsMiddle AgedPodocytesRenal Insufficiency, ChronicUp-RegulationMicroRNAsMIRN21 microRNA, humanbiomarkerCKDmiR-21miRNAurinary exosomes

Identifiers

PMID31066165
PMCPMC6584549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.