Evidence map›Paper›PMID 31065939›Full record

ArticleNatural products and bioprospecting2019

Chemical Constituents from Ethanoic Extracts of the Aerial Parts of Leea aequata L., a Traditional Folk Medicine of Myanmar.

Nay Lin Tun, Dong-Bao Hu, Meng-Yuan Xia, Dong-Dong Zhang, Jun Yang, Thaung Naing Oo, Yue-Hu Wang, Xue-Fei Yang

Open access · diamondAbstract read
In one paragraph

Article in Natural products and bioprospecting, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Hepatoprotective and Nephroprotective Effects ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nay Lin TunSoutheast Asia Biodiversity Research Institute, Chinese Academy of Sciences, Yezin, Nay Pyi Taw, 05282, Myanmar.
Dong-Bao HuCollege of Resources and Environment, Yuxi Normal University, Yuxi, 653100, People's Republic of China.
Meng-Yuan XiaKey Laboratory of Economic Plants and Biotechnology and the Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.
Dong-Dong ZhangSoutheast Asia Biodiversity Research Institute, Chinese Academy of Sciences, Yezin, Nay Pyi Taw, 05282, Myanmar.
Jun YangKey Laboratory of Economic Plants and Biotechnology and the Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.
Thaung Naing OoForest Research Institute, Yezin, Nay Pyi Taw, 05282, Myanmar.
Yue-Hu WangKey Laboratory of Economic Plants and Biotechnology and the Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China. wangyuehu@mail.kib.ac.cn.
Xue-Fei YangSoutheast Asia Biodiversity Research Institute, Chinese Academy of Sciences, Yezin, Nay Pyi Taw, 05282, Myanmar. xuefei@mail.kib.ac.cn.ORCID http://orcid.org/0000-0002-0986-2745
Kunming Institute of Botany · CNYezin Agricultural University · MMYuxi Normal University · CN

Funding

Southeast Asia Biodiversity Research Institute Chinese Academy of Sciences 2015CASEABRIRG001Southeast Asia Biodiversity Research Institute Chinese Academy of Sciences Y4ZK111B01The International Partnership Program of Chinese Academy of Sciences 153631KYSB20160004
6 · The paper itself

Abstract

We aimed at reporting the chemical constituents and antimicrobial activities of Leea aequata L., a traditional folk medicine used in Myanmar for the treatment of wounds and skin diseases. A new neolignan, (7S,8R)-9'-O-acetylcedrusin (1), a new lactam, (3S,4S)-4-chloro-3-hydroxypiperidin-2-one (2), along with 21 known compounds, including five lignans (3-7), four flavonoid glycosides (8-11), and others (12-23), were isolated from the ethanoic extract of the aerial parts of L. aequata. The structures of the new compounds were determined by NMR, MS, and ECD spectra. For all the antimicrobial tests of the 23 compounds, only 3,4,5-trihydroxybenzoic acid ethyl ester (17) showed weak inhibitory activities against Escherichia coli and Salmonella enterica subsp. enterica.

Indexed as

FlavonoidsLeea aequataLignansTraditional medicinesVitaceae

Identifiers

PMID31065939
PMCPMC6538738
OpenAlexW2944554140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.