Evidence map›Paper›PMID 31065907›Full record

ReviewCurrent oncology reports2019

Immunotherapy in Older Adults with Cancer.

Richard Curtis Godby, Douglas B Johnson, Grant R Williams

Abstract readReview
In one paragraph

Review in Current oncology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Immunotherapy in Older Patients with Cancer: A Narrative Review.International journal of general medicine · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Richard Curtis GodbyInternal Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Douglas B JohnsonDivision of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Grant R WilliamsDivision of Hematology/Oncology, Geriatrics, and Palliative Care, Institute of Cancer Outcomes and Survivorship, O'Neal Comprehensive Cancer Center at UAB, University of Alabama at Birmingham, 1600 7th Avenue South, Lowder 500, Birmingham, AL, 35233, USA. grwilliams@uabmc.edu.

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults with Colorectal Cancer: The M&M StudyK08CA234225 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, GRANT R · 2018 to 2022
$1.0M
Predicting and profiling long-term survival after immune checkpoint inhibitionK23CA204726 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JOHNSON, DOUGLAS B · 2016 to 2020
$756k
NCI NIH HHS K08 CA234225NCI NIH HHS K12 CA090625NCI NIH HHS K23 CA204726
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to examine the latest research and data on the use of immunotherapy in older adults with cancer in order to identify key gaps in the literature for future research. RECENT

findingsImmune checkpoint inhibitors are gaining approval and being incorporated into routine clinical use for numerous malignancies across age groups due to their overall efficacy and favorable side effect profiles. Although immune checkpoint inhibitors appear both safe and effective in older adults, deliberate study of immunotherapies in older adults is highly warranted given the paucity of data in a population with unique immunobiology that comprises the majority of the cancer population worldwide.

Indexed as

AdultAgedAged, 80 and overAge FactorsAntineoplastic Agents, ImmunologicalHumansImmunotherapyNeoplasmsPrognosisAntineoplastic Agents, ImmunologicalAgedClinical trial representationGeriatric oncologyImmune checkpoint inhibitorsImmunosenescenceImmunotherapy

Identifiers

PMID31065907
PMCPMC6619507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.