Evidence map›Paper›PMID 31065775›Full record

Observational studyWorld journal of surgery2019

Incidence, Risk Factors, and Natural Outcome of Vocal Fold Paresis in 920 Thyroid Operations with Routine Pre- and Postoperative Laryngoscopic Evaluation.

Maria Heikkinen, Kimmo Mäkinen, Elina Penttilä, Mari Qvarnström, Tatu Kemppainen, Heikki Löppönen, Jussi M Kärkkäinen

Open access · hybridAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. The impact of surgery type on the recovery of iatrogenic vocal fold injury.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  10. Giant toxic multinodular goiter with dyspnea: A case report.International journal of surgery case reports · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maria HeikkinenDepartment of Otorhinolaryngology, Head and Neck Surgery, Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0001-6220-9932
Kimmo MäkinenInstitute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Elina PenttiläDepartment of Otorhinolaryngology, Head and Neck Surgery, Kuopio University Hospital, Kuopio, Finland.
Mari QvarnströmDepartment of Phoniatrics, Kuopio University Hospital, Kuopio, Finland.
Tatu KemppainenDepartment of Otorhinolaryngology, Head and Neck Surgery, Kuopio University Hospital, Kuopio, Finland.
Heikki LöppönenDepartment of Otorhinolaryngology, Head and Neck Surgery, Kuopio University Hospital, Kuopio, Finland.
Jussi M KärkkäinenHeart Center, Kuopio University Hospital, PL 100, 70029, Kuopio, Finland. jkarkkai@gmail.com.
University of Eastern Finland · FIKuopio University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the incidence, risk factors, and spontaneous recovery rate of vocal fold paresis (VFP) with routine laryngoscopy before and after thyroid surgery.

methodsAll consecutive patients undergoing primary or redo thyroid surgery between years 2011-2016 were prospectively registered in an electronic database, and scheduled for pre- and postoperative laryngoscopic vocal fold inspection by otolaryngologists independently of the surgical team.

resultsA total of 920 thyroid operations with 1296 nerves at risk were performed in 866 patients. Pre- and postoperative laryngoscopy was done in 95% and 98%, respectively. Preoperative VFP was detected in 24 (2.8%) patients. New postoperative VFP was found in 53 of 920 operations (5.8%) and in 55 of 1296 nerves at risk (4.2%). After 12 months, 14 had recovered full vocal fold function and eight had near-complete recovery. VFP was permanent after 29 operations (3.2%); two patients were lost to follow-up with uncertain outcome. Of the 1296 nerves at risk, injury was permanent in 30 (2.3%). In multivariate analysis, patients operated for recurrent goiter had nearly nine times higher risk of new VFP (23% rate), whereas patients with malignant histology had three times higher risk of postoperative VFP (up to 22% rate).

conclusionVFP continues to be a serious complication of thyroid surgery, especially in operations for redo goiter and thyroid malignancy. The incidence of VFP may be underestimated unless laryngoscopic examinations are performed routinely.

Indexed as

LaryngoscopyAdultAgedFemaleGoiterHumansIncidenceMaleMiddle AgedPostoperative ComplicationsPreoperative PeriodRisk FactorsThyroid GlandThyroid NeoplasmsVocal Cord Paralysis

Identifiers

PMID31065775
OpenAlexW2944213094

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.