Evidence map›Paper›PMID 31065747›Full record

ArticleCellular and molecular life sciences : CMLS2019

The zinc-finger transcription factor MAZR regulates iNKT cell subset differentiation.

Maria Jonah Orola, Caroline Tizian, Ci Zhu, Liisa Andersen, Alexandra Franziska Gülich, Marlis Alteneder, Tatjana Stojakovic, Ursula Wiedermann, Michael Trauner, Wilfried Ellmeier and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Maria Jonah OrolaDivision of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.
Caroline TizianDivision of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.
Ci ZhuHans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, 1090, Vienna, Austria.
Liisa AndersenDivision of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.
Alexandra Franziska GülichDivision of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.
Marlis AltenederDivision of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.
Tatjana StojakovicClinical Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Graz, 8036, Graz, Austria.
Ursula WiedermannInstitute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.
Michael TraunerHans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, 1090, Vienna, Austria.
Wilfried EllmeierDivision of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.
Shinya SakaguchiDivision of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria. shinya.sakaguchi@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-0591-2469
Medical University of Vienna · AT

Funding

Austrian Science Fund MCCA W 1248-B30Austrian Science Fund P23641Austrian Science Fund P23669Austrian Science Fund P27747Austrian Science Fund P29790Austrian Science Fund SFB F4612-B28Austrian Science Fund W1212Austrian Science Fund FWF P 23641Austrian Science Fund FWF P 23669Austrian Science Fund FWF P 26193Austrian Science Fund FWF P 27747Austrian Science Fund FWF P 29790
6 · The paper itself

Abstract

Invariant natural killer T (iNKT) cells represent a subgroup of innate-like T cells and play an important role in immune responses against certain pathogens. In addition, they have been linked to autoimmunity and antitumor immunity. iNKT cells consist of several subsets with distinct functions; however, the transcriptional networks controlling iNKT subset differentiation are still not fully characterized. Myc-associated zinc-finger-related factor (MAZR, also known as PATZ1) is an essential transcription factor for CD8

Indexed as

AnimalsCell DifferentiationCells, CulturedGene Expression RegulationLymphocyte SubsetsMiceMice, Inbred C57BLMice, TransgenicNatural Killer T-CellsNeoplasm ProteinsRepressor ProteinsTranscription FactorsZinc FingersNeoplasm ProteinsRepressor ProteinsTranscription FactorsZfp278 protein, mouseiNKT cell functioniNKT cell subset differentiationPATZ1/MAZRTranscriptional regulation

Identifiers

PMID31065747
PMCPMC6803753
OpenAlexW2944621798

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.