ReviewDer Radiologe2019
[Intravenous lysis treatment in acute stroke treatment-latest situation].
Review in Der Radiologe, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
clinical issueIntravenous (i.v.) thrombolysis and mechanical thrombectomy are two essential pillars of acute stroke treatment in patients with vascular occlusion in the anterior circulation. The issue about using so-called bridging thrombolysis in acute stroke patients is increasingly under discussion.
resultsAfter application of i.v. thrombolysis treatment, stroke patients who were primarily transported to a neurovascular center and underwent timely endovascular treatment, showed a lower preinterventional recanalization rate, a lower 90-day mortality but no significant difference in the clinical outcome after 3 months compared with stroke patients with mechanical thrombectomy alone. Higher rates of intracranial hemorrhage could be detected in the bridging thrombolysis group of patients.
conclusionThe i.v. thrombolysis treatment is still an essential treatment concept in acute stroke management. Further studies should be carried out with respect to the application in mothership stroke patients undergoing early endovascular treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.